(Q40205438)

18 September 2017

Specific high affinity interactions of monomeric endotoxin.protein complexes with Toll-like receptor 4 ectodomain (English)

1 reference

18 September 2017

0 references

1 reference

7

Theresa L Gioannini

1 reference

18 September 2017

5

Athmane Teghanemt

1 reference

18 September 2017

1

Polonca Prohinar

1 reference

18 September 2017

4

DeSheng Zhang

1 reference

18 September 2017

6

Jerrold P Weiss

1 reference

18 September 2017

Fabio Re

2

1 reference

PubMed ID

17121827

18 September 2017

Richard Widstrom

series ordinal

3

1 reference

PubMed ID

17121827

18 September 2017

language of work or name

English

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publication date

22 November 2006

1 reference

Journal of Biological Chemistry

18 September 2017

8

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

18 September 2017

282

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18 September 2017

1010-1017

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18 September 2017

2

1 reference

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Innate recognition of lipopolysaccharide by CD14 and toll-like receptor 4-MD-2: unique roles for MD-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Innate immune responses to microbial poisons: discovery and function of the Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Monomeric endotoxin:protein complexes are essential for TLR4-dependent cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Recognition of gram-negative bacteria and endotoxin by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

MD-2 binds to bacterial lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Monomeric recombinant MD-2 binds toll-like receptor 4 tightly and confers lipopolysaccharide responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Isolation of an endotoxin-MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Construction of acetate auxotrophs of Neisseria meningitidis to study host-meningococcal endotoxin interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

An essential role for albumin in the interaction of endotoxin with lipopolysaccharide-binding protein and sCD14 and resultant cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Eukaryotic lipopolysaccharide deacylating enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Molecular basis of reduced potency of underacylated endotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Structure-function analysis of CD14 as a soluble receptor for lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Soluble CD14 truncated at amino acid 152 binds lipopolysaccharide (LPS) and enables cellular response to LPS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Endotoxin recognition and signal transduction by the TLR4/MD2-complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

CD14 is required for MyD88-independent LPS signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis in TLR4/MD-2/CD14 overexpressing CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Neisseria meningitidis lipooligosaccharide structure-dependent activation of the macrophage CD14/Toll-like receptor 4 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Lipopolysaccharide signaling in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Toll-like receptors as molecular switches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

Autophagy and plant innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609400200

21 January 2018

Identifiers

DOI

10.1074/JBC.M609400200

1 reference

18 September 2017

1 reference

PubMed ID

17121827