(Q40219964)

18 September 2017

The tandem BRCT domain of 53BP1 is not required for its repair function (English)

1 reference

18 September 2017

Irene Ward

1

1 reference

18 September 2017

Ja-Eun Kim

2

1 reference

18 September 2017

Kay Minn

3

1 reference

18 September 2017

Claudia C Chini

4

1 reference

18 September 2017

Georges Mer

5

1 reference

18 September 2017

Junjie Chen

6

1 reference

18 September 2017

language of work or name

English

0 references

publication date

16 October 2006

1 reference

Journal of Biological Chemistry

18 September 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

18 September 2017

281

1 reference

18 September 2017

38472-38477

1 reference

18 September 2017

50

1 reference

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

18 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

53BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

53BP1 is required for class switch recombination

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

53BP1, a mediator of the DNA damage checkpoint

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Megabase chromatin domains involved in DNA double-strand breaks in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Two cellular proteins that bind to wild-type but not mutant p53

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

53BP1 oligomerization is independent of its methylation by PRMT1.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Homo-oligomerization is the essential function of the tandem BRCT domains in the checkpoint protein Crb2.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853281

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

20 August 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607577200

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607577200

The BRCT Domain Is a Phospho-Protein Binding Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607577200

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M607577200

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17043355

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9-Rad9 interaction after DNA damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17043355

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M607577200

1 reference

18 September 2017

1 reference

18 September 2017

1 reference