(Q40227842)

18 September 2017

title

The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells (English)

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18 September 2017

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Tetyana Duka

1

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18 September 2017

Anita Sidhu

series ordinal

2

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18 September 2017

publication date

1 August 2006

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18 September 2017

published in

Neurotoxicity Research

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18 September 2017

volume

10

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18 September 2017

issue

1

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18 September 2017

page(s)

1-10

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https://scigraph.springernature.com/pub.10.1007/bf03033329

18 September 2017

exact match

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cites work

Tau and alpha-synuclein pathology in amygdala of Parkinsonism-dementia complex patients of Guam

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF03033329

Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF03033329

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

21 January 2018

1 reference

12 December 2020

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

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12 December 2020

Human alpha-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine.

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12 December 2020

Comparative analyses of alpha-synuclein expression levels in rat brain tissues and transfected cells

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12 December 2020

The role of alpha-synuclein in both neuroprotection and neurodegeneration

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12 December 2020

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

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12 December 2020

Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

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12 December 2020

17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions

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12 December 2020

Following the leader: fibrillization of alpha-synuclein and tau.

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12 December 2020

alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

1 reference

12 December 2020

Lewy bodies in progressive supranuclear palsy.

1 reference

12 December 2020

Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease.

1 reference

12 December 2020

Alterations of cytoskeletal tau protein of SH-SY5Y human neuroblastoma cells after exposure to MPTP.

1 reference

12 December 2020

Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies

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12 December 2020

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

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12 December 2020

Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

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12 December 2020

Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.

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12 December 2020

Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease

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12 December 2020

Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

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12 December 2020

Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation

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12 December 2020

Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions

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12 December 2020

MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells

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12 December 2020

Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells

1 reference

12 December 2020

14-3-3 binds to and mediates phosphorylation of microtubule-associated tau protein by Ser9-phosphorylated glycogen synthase kinase 3beta in the brain

1 reference

12 December 2020

Proteasomal inhibition by alpha-synuclein filaments and oligomers.

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12 December 2020

Degradation of alpha-synuclein by proteasome

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12 December 2020

Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice

1 reference

12 December 2020

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

12 December 2020

Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells

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12 December 2020

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

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12 December 2020

Proteasome inhibition causes nigral degeneration with inclusion bodies in rats

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12 December 2020

Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration

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12 December 2020

14-3-3 Protein mediates phosphorylation of microtubule-associated protein tau by serum- and glucocorticoid-induced protein kinase 1.

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12 December 2020

Induction of alpha-synuclein aggregation by intracellular nitrative insult.

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12 December 2020

Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells

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12 December 2020

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

1 reference

12 December 2020

Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry.

1 reference

12 December 2020

Attenuation of dopamine transporter activity by alpha-synuclein

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12 December 2020

Co-occurrence of Parkinson's disease with progressive supranuclear palsy.

1 reference

12 December 2020

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

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12 December 2020

Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein

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12 December 2020

Measurement of cell death

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12 December 2020

Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

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12 December 2020

Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates

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12 December 2020

14-3-3 proteins in neuronal development and function

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12 December 2020

Autophagy as a regulated pathway of cellular degradation

1 reference

12 December 2020

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

1 reference

12 December 2020

Parkinson's disease: mechanisms and models

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12 December 2020

Identifiers

DOI

10.1007/BF03033329

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18 September 2017

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