(Q40267951)

19 September 2017

title

Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1. (English)

1 reference

19 September 2017

author

Daniele Guardavaccaro

object named as

Daniele Guardavaccaro

5

0 references

Michele Pagano

object named as

Michele Pagano

6

0 references

author name string

Peng Ji

1

1 reference

19 September 2017

Luba Goldin

2

1 reference

19 September 2017

Hao Ren

3

1 reference

19 September 2017

Daqian Sun

4

1 reference

19 September 2017

Liang Zhu

7

1 reference

19 September 2017

language of work or name

English

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publication date

14 June 2006

1 reference

Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

issue

33

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19 September 2017

page(s)

24058-24069

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Regulation of the cell cycle by SCF-type ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors

21 January 2018

1 reference

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An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2

21 January 2018

1 reference

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Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

21 January 2018

1 reference

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Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

21 January 2018

1 reference

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Inhibition of cyclin-dependent kinases by p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Three different binding sites of Cks1 are required for p27-ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Noncatalytic requirement for cyclin A-cdk2 in p27 turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603105200

21 January 2018

Identifiers

DOI

10.1074/JBC.M603105200

1 reference

19 September 2017

1 reference