(Q40271340)

19 September 2017

title

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation (English)

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G protein-coupled receptor

19 September 2017

main subject

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author

Martin Christian Michel

9

object named as

Martin C Michel

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19 September 2017

author name string

Maider López De Jesús

1

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19 September 2017

Matthias B Stope

2

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19 September 2017

Paschal A Oude Weernink

3

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19 September 2017

Yvonne Mahlke

4

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19 September 2017

Christof Börgermann

5

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19 September 2017

Viktoria N Ananaba

6

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19 September 2017

Christian Rimmbach

7

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19 September 2017

Dieter Rosskopf

8

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19 September 2017

Karl H Jakobs

10

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19 September 2017

Martina Schmidt

11

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19 September 2017

language of work or name

English

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publication date

5 June 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

issue

31

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19 September 2017

page(s)

21837-21847

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Heterologous expression and characterization of the human R-ras gene product

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

21 January 2018

1 reference

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Integration of calcium and Ras signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

21 January 2018

1 reference

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Ras GTPases: integrins' friends or foes?

21 January 2018

1 reference

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GAP control: regulating the regulators of small GTPases

21 January 2018

1 reference

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Integrin activation by R-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

The small GTP-binding protein R-Ras can influence integrin activation by antagonizing a Ras/Raf-initiated integrin suppression pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

R-Ras alters Ca2+ homeostasis by increasing the Ca2+ leak across the endoplasmic reticular membrane.

21 January 2018

1 reference

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An Eph receptor regulates integrin activity through R-Ras

21 January 2018

1 reference

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A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A

21 January 2018

1 reference

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Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity

21 January 2018

1 reference

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Linking Rap to cell adhesion

21 January 2018

1 reference

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The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras

21 January 2018

1 reference

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R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho

21 January 2018

1 reference

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The unique N-terminus of R-ras is required for Rac activation and precise regulation of cell migration

21 January 2018

1 reference

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R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis

21 January 2018

1 reference

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Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

21 January 2018

1 reference

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CalDAG-GEFIII activation of Ras, R-ras, and Rap1.

21 January 2018

1 reference

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Crk activation of JNK via C3G and R-Ras

21 January 2018

1 reference

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p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

21 January 2018

1 reference

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Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B

21 January 2018

1 reference

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A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

21 January 2018

1 reference

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Inhibition of phospholipase C-ε by Gi-coupled receptors

21 January 2018

1 reference

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Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

The ADP-ribosylation factor (ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase D

21 January 2018

1 reference

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cAMP-GEFII is a direct target of cAMP in regulated exocytosis

21 January 2018

1 reference

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p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene

21 January 2018

1 reference

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Retroviral delivery of small interfering RNA into primary cells

21 January 2018

1 reference

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Muscarinic receptor-stimulated cytosol-membrane translocation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Epac: a new cAMP target and new avenues in cAMP research

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

ADP ribosylation of Arg41 of Rap by ExoS inhibits the ability of Rap to interact with its guanine nucleotide exchange factor, C3G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Phospholipase D stimulation by receptor tyrosine kinases mediated by protein kinase C and a Ras/Ral signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604156200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604156200

1 reference

19 September 2017

1 reference