(Q40284379)

19 September 2017

title

Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy (English)

1 reference

19 September 2017

9

1 reference

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7 June 2020

Marijke Brink

12

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7 June 2020

author name string

Pankaj Shende

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598511%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Lifen Xu

2

1 reference

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7 June 2020

Christian Morandi

3

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7 June 2020

Laura Pentassuglia

4

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7 June 2020

Philippe Heim

5

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7 June 2020

Sonia Lebboukh

6

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7 June 2020

Thierry Pedrazzini

8

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7 June 2020

Michael N Hall

10

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7 June 2020

Markus A Rüegg

11

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7 June 2020

Corinne Berthonneche

7

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7 June 2020

publication date

23 November 2015

1 reference

19 September 2017

published in

Cardiovascular Research

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7 June 2020

volume

109

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7 June 2020

issue

1

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7 June 2020

page(s)

103-114

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Mammalian target of rapamycin signaling in cardiac physiology and disease.

7 June 2020

cites work

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Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

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Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology

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mTORC2 controls actin polymerization required for consolidation of long-term memory.

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Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.

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Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

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Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

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Early changes in excitation-contraction coupling: transition from compensated hypertrophy to failure in Dahl salt-sensitive rat myocytes.

21 January 2018

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Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

21 January 2018

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Temporally regulated and tissue-specific gene manipulations in the adult and embryonic heart using a tamoxifen-inducible Cre protein

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PKC-delta and PKC-epsilon: foes of the same family or strangers?

21 January 2018

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

21 January 2018

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Myocardial AKT: the omnipresent nexus

21 January 2018

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Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

21 January 2018

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mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α

21 January 2018

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mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

21 January 2018

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Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

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Serum and glucocorticoid-responsive kinase-1 regulates cardiomyocyte survival and hypertrophic response

21 January 2018

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Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growth

21 January 2018

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21 January 2018

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21 January 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

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The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Regulation of mTOR and S6K1 activation by the nPKC isoforms, PKCepsilon and PKCdelta, in adult cardiac muscle cells

21 January 2018

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Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes

21 January 2018

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Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/CVR/CVV252

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598511%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference