(Q40290768)

19 September 2017

title

Hdm2 nuclear export, regulated by insulin-like growth factor-I/MAPK/p90Rsk signaling, mediates the transformation of human cells (English)

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19 September 2017

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Mark W Jackson

1

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19 September 2017

Linnea E Patt

2

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19 September 2017

Gretchen A LaRusch

3

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19 September 2017

David B Donner

4

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19 September 2017

George R Stark

5

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19 September 2017

Lindsey D Mayo

6

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19 September 2017

language of work or name

English

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publication date

18 April 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

issue

24

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19 September 2017

page(s)

16814-16820

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19 September 2017

cites work

Surfing the p53 network

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https://api.crossref.org/works/10.1074%2FJBC.M511617200

The p53 pathway: positive and negative feedback loops

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https://api.crossref.org/works/10.1074%2FJBC.M511617200

Phosphorylation of HDM2 by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

P53 licensed to kill? Operating the assassin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511617200

Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy

21 January 2018

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Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511617200

Insulin-like growth factor I induces MDM2-dependent degradation of p53 via the p38 MAPK pathway in response to DNA damage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511617200

HDM2 phosphorylation by MAPKAP kinase 2.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M511617200

Regulation of p53 expression by the RAS-MAP kinase pathway

21 January 2018

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Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

21 January 2018

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Transformation of normal human cells in the absence of telomerase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

Association of insulin-like growth-factor-I-induced DNA synthesis with phosphorylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M511617200

21 January 2018

Identifiers

DOI

10.1074/JBC.M511617200

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19 September 2017

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