(Q40300478)

19 September 2017

title

The role of histone acetylation versus DNA damage in drug-induced senescence and apoptosis (English)

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19 September 2017

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Rebbaa A

1

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19 September 2017

Zheng X

series ordinal

2

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19 September 2017

Chu F

series ordinal

3

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19 September 2017

Mirkin BL

series ordinal

4

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19 September 2017

publication date

24 March 2006

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Cell Death & Differentiation

19 September 2017

published in

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19 September 2017

volume

13

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19 September 2017

issue

11

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19 September 2017

page(s)

1960-1967

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Emerging roles for chromatin remodeling in cancer biology

19 September 2017

cites work

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Caspase inhibition switches doxorubicin-induced apoptosis to senescence

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DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

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7 January 2021

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

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Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases

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Assessment of histone H2AX phosphorylation induced by DNA topoisomerase I and II inhibitors topotecan and mitoxantrone and by the DNA cross-linking agent cisplatin

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DNA double-strand breaks: signaling, repair and the cancer connection

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7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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7 January 2021

Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter

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Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.

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7 January 2021

MDR1, chemotherapy and chromatin remodeling.

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7 January 2021

DNA damage detection and repair, and the involvement of epigenetic states.

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7 January 2021

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

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7 January 2021

Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

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7 January 2021

Relationship between lethal effects and topoisomerase II-mediated double-stranded DNA breaks produced by anthracyclines with different sequence specificity

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7 January 2021

Differential single- versus double-strand DNA breakage produced by doxorubicin and its morpholinyl analogues

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7 January 2021

Caspase 3-mediated cleavage of p21WAF1/CIP1 associated with the cyclin A-cyclin-dependent kinase 2 complex is a prerequisite for apoptosis in SK-HEP-1 cells

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7 January 2021

Cisplatin induces apoptosis in a human ovarian carcinoma cell line without concomitant internucleosomal degradation of DNA.

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7 January 2021

Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock

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7 January 2021

Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene

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7 January 2021

DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling

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7 January 2021

Histone Deacetylation of RB-Responsive Promoters: Requisite for Specific Gene Repression but Dispensable for Cell Cycle Inhibition

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7 January 2021

Factors secreted by human neuroblastoma mediated doxorubicin resistance by activating STAT3 and inhibiting apoptosis

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7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401895

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Dimensions Publication ID

19 September 2017

1030496674

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1 reference