(Q40335919)

English

A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation

scientific article published on 26 December 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

lipopolysaccharide

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Anhidrotic ectodermal dysplasia

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

4

object named as

Alain Israël

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Emilie Vinolo

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Hélène Sebban

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Alain Chaffotte

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Gilles Courtois

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Michel Véron

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Fabrice Agou

7

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

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publication date

26 December 2005

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Europe PubMed Central

PubMed publication ID

19 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

19 September 2017

281

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Europe PubMed Central

PubMed publication ID

19 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

6334-6348

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Signaling to NF-kappaB

1 reference

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21 January 2018

The NF-kappaB signaling pathway in human genetic diseases

1 reference

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21 January 2018

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

1 reference

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21 January 2018

A recurrent deletion in the ubiquitously expressed NEMO (IKK-gamma) gene accounts for the vast majority of incontinentia pigmenti mutations

1 reference

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21 January 2018

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO)

1 reference

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21 January 2018

Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia

1 reference

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21 January 2018

Nuclear factor kappaB essential modulator-deficient child with immunodeficiency yet without anhidrotic ectodermal dysplasia

1 reference

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21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

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21 January 2018

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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21 January 2018

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

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21 January 2018

An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways

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21 January 2018

Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization

1 reference

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21 January 2018

vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma

1 reference

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21 January 2018

Stimulation of IKK-gamma oligomerization by the human T-cell leukemia virus oncoprotein Tax.

1 reference

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21 January 2018

Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma

1 reference

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21 January 2018

Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation

1 reference

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21 January 2018

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

1 reference

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21 January 2018

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

1 reference

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21 January 2018

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

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21 January 2018

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

1 reference

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21 January 2018

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

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21 January 2018

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

NEMO trimerizes through its coiled-coil C-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

The trimerization domain of NEMO is composed of the interacting C-terminal CC2 and LZ coiled-coil subdomains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

The zinc finger mutation C417R of I-kappa B kinase gamma impairs lipopolysaccharide- and TNF-mediated NF-kappa B activation through inhibiting phosphorylation of the I-kappa B kinase beta activation loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510118200

21 January 2018

Calculation of protein extinction coefficients from amino acid sequence data

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21 January 2018

A self-consistent method for the analysis of protein secondary structure from circular dichroism.

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Structure of crystalline D-Tyr-tRNA(Tyr) deacylase. A representative of a new class of tRNA-dependent hydrolases

1 reference

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21 January 2018

Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kappaB activation

1 reference

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21 January 2018

Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein

1 reference

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21 January 2018

Study of the "molten globule" intermediate state in protein folding by a hydrophobic fluorescent probe

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Structural classification of zinc fingers: survey and summary

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A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped.

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Use of high-speed size-exclusion chromatography for the study of protein folding and stability

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Influence of mRNA self-structure on hybridization: computational tools for antisense sequence selection.

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Effect of alanine versus glycine in alpha-helices on protein stability

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Unfolding of a leucine zipper is not a simple two-state transition

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Solution structures of two CCHC zinc fingers from the FOG family protein U-shaped that mediate protein-protein interactions

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Aromatic-aromatic interactions in the zinc finger motif. Analysis of the two-dimensional nuclear magnetic resonance structure of a mutant domain

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21 January 2018

The hidden thermodynamics of a zinc finger

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Protein degradation and protection against misfolded or damaged proteins

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

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21 January 2018

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

1 reference

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21 January 2018

Regulation of the NF-kappaB activation pathway by isolated domains of FIP3/IKKgamma, a component of the IkappaB-alpha kinase complex

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21 January 2018

Human nuclear factor kappa B essential modulator mutation can result in immunodeficiency without ectodermal dysplasia

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M510118200

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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