(Q40369817)

19 September 2017

title

Targeted induction of apoptosis by chimeric granzyme B fusion proteins carrying antibody and growth factor domains for cell recognition (English)

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19 September 2017

3

1 reference

19 September 2017

Dälken B

1

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19 September 2017

Giesübel U

series ordinal

2

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19 September 2017

Wels WS

series ordinal

4

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19 September 2017

publication date

1 April 2006

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Cell Death & Differentiation

19 September 2017

published in

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19 September 2017

volume

13

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19 September 2017

issue

4

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19 September 2017

page(s)

576-585

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401773

19 September 2017

exact match

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cites work

Construction and functional characterization of scFv(14E1)-ETA - a novel, highly potent antibody-toxin specific for the EGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

Cytotoxic T lymphocytes: all roads lead to death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Lymphocyte-mediated cytotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Granzyme B mimics apical caspases. Description of a unified pathway for trans-activation of executioner caspase-3 and -7.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

A central role for Bid in granzyme B-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

The ErbB signaling network: receptor heterodimerization in development and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Untangling the ErbB signalling network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

The EGF receptor family as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Recombinant immunotoxins and retargeted killer cells: employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Killing of target cells by redirected granzyme B in the absence of perforin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Conversion of the substrate specificity of mouse proteinase granzyme B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Activation of EGF receptor family members suppresses the cytotoxic effects of tumor necrosis factor-alpha.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Membrane receptors are not required to deliver granzyme B during killer cell attack

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Tumor therapeutics by design: targeting and activation of death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Secreted antibody/granzyme B fusion protein stimulates selective killing of HER2-overexpressing tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

The in vivo use of chloroquine to promote non-viral gene delivery to the liver via the portal vein and bile duct

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Bisquinoline antimalarials: their role in malaria chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Endocytosing the death sentence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Nuclear export is evolutionarily conserved in CVC paired-like homeobox proteins and influences protein stability, transcriptional activation, and extracellular secretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401773

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401773

1 reference

Dimensions Publication ID

19 September 2017

1042281886

0 references

1 reference