Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q40372954)
Watch
English
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection.
scientific article published on 13 January 2017
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
title
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
author
Selma Tuzlak
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Robyn L Schenk
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Ajithkumar Vasanthakumar
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Simon Preston
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Axel Kallies
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Andreas Strasser
series ordinal
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Marco J Herold
series ordinal
10
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
author name string
Manuel D Haschka
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Dimitra Zotos
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Andreas Villunger
series ordinal
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
publication date
13 January 2017
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
volume
24
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
page(s)
523-533
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
exact match
https://scigraph.springernature.com/pub.10.1038/cdd.2016.155
0 references
cites work
BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Antagonism between MCL-1 and PUMA governs stem/progenitor cell survival during hematopoietic recovery from stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Knockdown of the antiapoptotic Bcl-2 family member A1/Bfl-1 protects mice from anaphylaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Regulation of A1 by OX40 contributes to CD8(+) T cell survival and anti-tumor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Mcl-1 antagonizes Bax/Bak to promote effector CD4(+) and CD8(+) T-cell responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Expanding roles for CD4⁺ T cells in immunity to viruses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Bid and Bim collaborate during induction of T cell death in persistent infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Mcl-1; the molecular regulation of protein function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
The costimulation-regulated duration of PKB activation controls T cell longevity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
IL-7 is critical for homeostatic proliferation and survival of naive T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Expression of the Bcl-2 family member A1 is developmentally regulated in T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Virus-specific CD8+ T cells in primary and secondary influenza pneumonia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Multiple gene duplication and expression of mouse bcl-2-related genes, A1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
17 June 2018
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
Characterisation of a novel A1-specific monoclonal antibody.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
Continuous T cell receptor signals maintain a functional regulatory T cell pool.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
MCL-1 but not BCL-XL is critical for the development and sustained expansion of thymic lymphoma in p53-deficient mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
Bcl-2 allows effector and memory CD8+ T cells to tolerate higher expression of Bim.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
The stability and anti-apoptotic function of A1 are controlled by its C terminus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
The antiapoptotic protein Bcl-xL is dispensable for the development of effector and memory T lymphocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5344212
retrieved
20 August 2018
A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2016.155
retrieved
21 January 2018
CD3-mediated apoptosis of human medullary thymocytes and activated peripheral T cells: respective roles of interleukin-1, interleukin-2, interferon-gamma and accessory cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDD.2016.155
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/CDD.2016.155
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Dimensions Publication ID
1050545335
0 references
PMC publication ID
5344212
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
PubMed publication ID
28085151
1 reference
stated in
Europe PubMed Central
PMC publication ID
5344212
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28085151%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 April 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit