(Q40374564)

19 September 2017

title

The role of Polo-like kinase 1 in the inhibition of centrosome separation after ionizing radiation (English)

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19 September 2017

Wei Zhang

1

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19 September 2017

Lynda Fletcher

series ordinal

2

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19 September 2017

Ruth J Muschel

series ordinal

3

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19 September 2017

language of work or name

English

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publication date

12 September 2005

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

280

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19 September 2017

issue

52

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19 September 2017

page(s)

42994-42999

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Cell cycle checkpoints: preventing an identity crisis

19 September 2017

cites work

1 reference

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DNA damage checkpoint control in cells exposed to ionizing radiation

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The G2-phase DNA-damage checkpoint

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rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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The centrosome in vertebrates: more than a microtubule-organizing center

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Centrosome separation: respective role of microtubules and actin filaments

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Drosophila checkpoint kinase 2 couples centrosome function and spindle assembly to genomic integrity

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Polo-like kinases: positive regulators of cell division from start to finish.

21 January 2018

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Polo-like kinases: a team that plays throughout mitosis

21 January 2018

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Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

21 January 2018

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The polo-like kinase Plx1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes

21 January 2018

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Regulating the onset of mitosis

21 January 2018

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Checking out the G(2)/M transition.

21 January 2018

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PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression.

21 January 2018

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The cyclin-ubiquitin ligase activity of cyclosome/APC is jointly activated by protein kinases Cdk1-cyclin B and Plk.

21 January 2018

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Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

21 January 2018

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Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

21 January 2018

1 reference

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Substrate specificity and cell cycle regulation of the Nek2 protein kinase, a potential human homolog of the mitotic regulator NIMA of Aspergillus nidulans.

21 January 2018

1 reference

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A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

21 January 2018

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The Nek2 protein kinase: a novel regulator of centrosome structure

21 January 2018

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Alternative splice variants of the human centrosome kinase Nek2 exhibit distinct patterns of expression in mitosis

21 January 2018

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Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles

21 January 2018

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21 January 2018

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C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2

21 January 2018

1 reference

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Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation

21 January 2018

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DNA damage in HeLa cells induced arrest at a discrete point in G2 phase as defined by CENP-F localization

21 January 2018

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Plk is a functional homolog of Saccharomyces cerevisiae Cdc5, and elevated Plk activity induces multiple septation structures

21 January 2018

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Caffeine inhibits the checkpoint kinase ATM

21 January 2018

1 reference

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APC/C-mediated destruction of the centrosomal kinase Nek2A occurs in early mitosis and depends upon a cyclin A-type D-box

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505450200

Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505450200

Inhibition of Centrosome Separation after DNA Damage: A Role for Nek2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505450200

Polo-like kinase-1 is a target of the DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505450200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505450200

1 reference

19 September 2017

1 reference