(Q40386857)

20 September 2017

title

Roles of tyrosine residues 845, 892 and 922 in constitutive activation of murine FLT3 kinase domain mutant (English)

1 reference

20 September 2017

Jun Ishiko

1

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20 September 2017

Masao Mizuki

2

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20 September 2017

Itaru Matsumura

3

1 reference

20 September 2017

Hirohiko Shibayama

4

1 reference

20 September 2017

Hiroyuki Sugahara

5

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20 September 2017

Glen Scholz

6

1 reference

20 September 2017

Hubert Serve

7

1 reference

20 September 2017

Yuzuru Kanakura

8

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20 September 2017

language of work or name

English

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publication date

1 December 2005

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20 September 2017

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20 September 2017

volume

24

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20 September 2017

issue

55

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20 September 2017

page(s)

8144-8153

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Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Phosphatidylinositol-3' kinase is not required for mitogenesis or internalization of the Flt3/Flk2 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Constitutive activation of FLT3 in acute myeloid leukaemia and its consequences for growth of 32D cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

The structural basis for autoinhibition of FLT3 by the juxtamembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Necessity of tyrosine 719 and phosphatidylinositol 3'-kinase-mediated signal pathway in constitutive activation and oncogenic potential of c-kit receptor tyrosine kinase with the Asp814Val mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

PDGFRA activating mutations in gastrointestinal stromal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Plat-E: an efficient and stable system for transient packaging of retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Class III receptor tyrosine kinases: role in leukaemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

p50(Cdc37) can buffer the temperature-sensitive properties of a mutant of Hck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Constitutive activation of c-kit by the juxtamembrane but not the catalytic domain mutations is inhibited selectively by tyrosine kinase inhibitors STI571 and AG1296.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

7 January 2021

Incidence and prognosis of c-KIT and FLT3 mutations in core binding factor (CBF) acute myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

7 January 2021

Genetic lesions involved in temperature sensitivity of the src gene products of four Rous sarcoma virus mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

7 January 2021

Clinical correlates of the presence of the Asp816Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208957

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208957

1 reference

Dimensions Publication ID

20 September 2017

1047712504

0 references

1 reference