(Q40405256)

English

An oncolytic adenovirus controlled by a modified telomerase promoter is attenuated in telomerase-negative cells, but shows reduced activity in cancer cells

scientific article published on 23 June 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

An oncolytic adenovirus controlled by a modified telomerase promoter is attenuated in telomerase-negative cells, but shows reduced activity in cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

oncolytic virus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

S Bortolanza

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

C Qian

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

M G Kramer

3

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

C Gomar

4

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

F Farinati

6

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

R Hernandez-Alcoceba

7

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

publication date

23 June 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Journal of Molecular Medicine

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Europe PubMed Central

PubMed publication ID

20 September 2017

83

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Europe PubMed Central

PubMed publication ID

20 September 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

736-747

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Rb and E2F-1 regulate telomerase activity in human cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00109-005-0681-1

21 January 2018

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase-dependent oncolytic adenovirus for cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase-specific replication-selective virotherapy for human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ad-mTERT-delta19, a conditional replication-competent adenovirus driven by the human telomerase promoter, selectively replicates in and elicits cytopathic effect in a cancer cell-specific manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small-molecule-based identification of dynamic assembly of E2F-pocket protein-histone deacetylase complex for telomerase regulation in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenoviral gene transfer of interleukin 12 into tumors synergizes with adoptive T cell therapy both at the induction and effector level

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the human telomerase reverse transcriptase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo comparative study of chimeric liver-specific promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel conditionally replicative adenovirus vector targeting telomerase-positive tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple tumor suppressor pathways negatively regulate telomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase maintains telomere structure in normal human cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E1B-55K-deleted adenovirus expressing E1A-13S by AFP-enhancer/promoter is capable of highly specific replication in AFP-producing hepatocellular carcinoma and eradication of established tumor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent antitumoral efficacy of a novel replicative adenovirus CNHK300 targeting telomerase-positive cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel oncolytic adenovirus targeting to telomerase activity in tumor cells with potent

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human telomerase and its regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simplified system for generating recombinant adenoviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase catalytic subunit homologs from fission yeast and human

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downstream E-box-mediated regulation of the human telomerase reverse transcriptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A survey of telomerase activity in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of an adenoviral vector controlled by the human telomerase reverse transcriptase promoter causes tumor-selective tumor lysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A telomerase-dependent conditionally replicating adenovirus for selective treatment of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hayflick, his limit, and cellular ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beginning to understand the end of the chromosome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Switching and signaling at the telomere

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of the human telomerase gene CpG island

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal human chromosomes have long G-rich telomeric overhangs at one end

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase activation by histone deacetylase inhibitor in normal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of sensitivity to ganciclovir in human hepatocellular carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression profile of the putative catalytic subunit of the telomerase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F-1 represses transcription of the human telomerase reverse transcriptase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15976917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00109-005-0681-1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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