(Q40408475)

20 September 2017

Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells (English)

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20 September 2017

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1 reference

1 reference

Siddharth Kaul

1

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20 September 2017

Vellareddy Anantharam

2

1 reference

20 September 2017

Yongjie Yang

3

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20 September 2017

Christopher J Choi

4

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20 September 2017

Arthi Kanthasamy

5

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20 September 2017

Anumantha G Kanthasamy

6

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20 September 2017

language of work or name

English

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publication date

16 June 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

31

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20 September 2017

28721-28730

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Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Role of Proteolytic Activation of Protein Kinase Cδ in Oxidative Stress-Induced Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Genetics, lifestyle and the roles of amyloid beta and oxidative stress in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Molecular Pathways of Neurodegeneration in Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Oxidative stress in neurodegeneration: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Oxidative stress in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Development of a rapid approach to identification of tyrosine phosphorylation sites: application to PKC delta phosphorylated upon activation of the high affinity receptor for IgE in rat basophilic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Protein kinase C delta (PKC delta): activation mechanisms and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Downregulating PKC delta provides a PI3K/Akt-independent survival signal that overcomes apoptotic signals generated by c-Src overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Interaction between protein kinase C delta and the c-Abl tyrosine kinase in the cellular response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Stimulus-specific differences in protein kinase C delta localization and activation mechanisms in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Efficacy of grafted immortalized dopamine neurons in an animal model of parkinsonism: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Oxidative stress to dopaminergic neurons as models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

The role of H2O2 as a mediator of UVB-induced apoptosis in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Involvement of cytochrome c release and caspase-3 activation in the oxidative stress-induced apoptosis in human tendon fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Selenium has a protective role in caspase-3-dependent apoptosis induced by H2O2 in primary cultured pig thyrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Fas-induced DNA fragmentation and proteolysis of nuclear proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Activation of delta-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Roles of protein kinase C delta in the accumulation of P53 and the induction of apoptosis in H2O2-treated bovine endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Novel protein kinase C delta isoform insensitive to caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

The activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Identification of tyrosine 187 as a protein kinase C-delta phosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Activation of protein kinase C by tyrosine phosphorylation in response to H2O2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Suppressive Effects of Genistein on Oxidative Stress and NFκB Activation in RAW 264.7 Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: implications for oxidative stress and environmental factors in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501092200

21 January 2018

Identifiers

DOI

10.1074/JBC.M501092200

1 reference

20 September 2017

1 reference