(Q40420028)

20 September 2017

title

The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN. (English)

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20 September 2017

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Bhuvanesh Dave

1

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20 September 2017

Renea R Eason

2

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20 September 2017

S Renée Till

3

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20 September 2017

Yan Geng

4

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20 September 2017

Michael C Velarde

5

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20 September 2017

Thomas M Badger

6

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20 September 2017

Rosalia C M Simmen

7

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20 September 2017

language of work or name

English

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publication date

19 May 2005

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20 September 2017

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20 September 2017

volume

26

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20 September 2017

issue

10

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20 September 2017

page(s)

1793-1803

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20 September 2017

cites work

Cancer statistics, 2003.

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Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis

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Breast cancer genetics: what we know and what we need

21 January 2018

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Maternal nutrition, fetal nutrition, and disease in later life

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Population-based case-control study of soyfood intake and breast cancer risk in Shanghai

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Adolescent and adult soy intake and risk of breast cancer in Asian-Americans

21 January 2018

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Mechanisms of cancer chemoprevention by soy isoflavone genistein

21 January 2018

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Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta

21 January 2018

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Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta

21 January 2018

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Phyto-oestrogens, their mechanism of action: current evidence for a role in breast and prostate cancer

21 January 2018

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Mechanism for the suppression of the mammalian stress response by genistein, an anticancer phytoestrogen from soy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Mechanisms of apoptosis avoidance in cancer.

21 January 2018

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Apoptosis and tumourigenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Apoptosis-based therapies

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

PTEN deficiency: a role in mammary carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model

21 January 2018

1 reference

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Tumorigenesis facilitated by Pten deficiency in the skin: evidence of p53-Pten complex formation on the initiation phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Inhibition of NMU-induced mammary tumorigenesis by dietary soy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Altered mammary gland differentiation and progesterone receptor expression in rats fed soy and whey proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Uterine phenotype of young adult rats exposed to dietary soy or genistein during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Phosphorylation of the PTEN tail regulates protein stability and function

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Suppression of PTEN expression by NF-kappa B prevents apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Immunonutrition and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Stem cells in normal breast development and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Towards an integrated model for breast cancer etiology: the crucial role of the number of mammary tissue-specific stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Isolation and characterization of functional mammary gland stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGI131

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGI131

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20 September 2017

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