(Q35959363)

11 August 2017

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title

Genetic and epigenetic changes in mammary epithelial cells may mimic early events in carcinogenesis (English)

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11 August 2017

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7

Krystyna Kozakiewicz

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11 August 2017

Thea D Tlsty

1

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11 August 2017

Yongping G Crawford

2

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11 August 2017

Charles R Holst

3

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11 August 2017

Colleen A Fordyce

4

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11 August 2017

Jianmin Zhang

5

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11 August 2017

Kimberly McDermott

6

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11 August 2017

Mona L Gauthier

8

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11 August 2017

language of work or name

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1 July 2004

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Journal of Mammary Gland Biology and Neoplasia

11 August 2017

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11 August 2017

9

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11 August 2017

263-274

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11 August 2017

3

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https://scigraph.springernature.com/pub.10.1023/b:jomg.0000048773.95897.5f

11 August 2017

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cites work

Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells

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12 December 2020

Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.

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12 December 2020

Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program

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Two types of normal human breast epithelial cells derived from reduction mammoplasty: phenotypic characterization and response to SV40 transfection

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Breast cancer and atypia among young and middle-aged women: a study of 110 medicolegal autopsies

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Growth suppression by p16ink4 requires functional retinoblastoma protein

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Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract

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12 December 2020

In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis

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12 December 2020

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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12 December 2020

Normal human fibroblasts are resistant to RAS-induced senescence

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12 December 2020

Gradual phenotypic conversion associated with immortalization of cultured human mammary epithelial cells

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12 December 2020

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation.

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12 December 2020

Cyclooxygenase-2: a target for the prevention and treatment of breast cancer

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12 December 2020

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells

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12 December 2020

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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12 December 2020

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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12 December 2020

Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies

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12 December 2020

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

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12 December 2020

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

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12 December 2020

Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing

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12 December 2020

Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis

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12 December 2020

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

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12 December 2020

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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12 December 2020

Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma

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12 December 2020

Distinctive traits of normal and tumor-derived human mammary epithelial cells expressed in a medium that supports long-term growth of both cell types

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12 December 2020

Rates of p16 (MTS1) mutations in primary tumors with 9p loss

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12 December 2020

Chromosome abnormalities in bilateral breast carcinomas. Cytogenetic evaluation of the clonal origin of multiple primary tumors.

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12 December 2020

Creation of human tumour cells with defined genetic elements

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12 December 2020

Linoleate metabolites enhance the in vitro proliferative response of mouse mammary epithelial cells to epidermal growth factor

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12 December 2020

Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells.

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12 December 2020

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

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12 December 2020

Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium.

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12 December 2020

Mutations of Bacteria from Virus Sensitivity to Virus Resistance

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12 December 2020

Analysis of p16INK4aand Its Interaction with CDK4

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12 December 2020

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

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12 December 2020

TRF2 Protects Human Telomeres from End-to-End Fusions

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12 December 2020

The prevalence of carcinoma in situ in normal and cancer-associated breasts

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12 December 2020

Chromosome analyses of human mammary epithelial cells at stages of chemical-induced transformation progression to immortality

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12 December 2020

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

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12 December 2020

Human papillomavirus type 16 E7 alleviates a proliferation block in early passage human mammary epithelial cells

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12 December 2020

Extension of life-span by introduction of telomerase into normal human cells

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12 December 2020

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

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12 December 2020

Cytogenetics of epithelial hyperplasias of the human breast

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12 December 2020

Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium

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12 December 2020

Inactivation of p16 in human mammary epithelial cells by CpG island methylation

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12 December 2020

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

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12 December 2020

Using autopsy series to estimate the disease "reservoir" for ductal carcinoma in situ of the breast: how much more breast cancer can we find?

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12 December 2020

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

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12 December 2020

Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.

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12 December 2020

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12 December 2020

Genetic induction and upregulation of cyclooxygenase (COX) and aromatase (CYP19): an extension of the dietary fat hypothesis of breast cancer

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12 December 2020

The contributions of cyclooxygenase-2 to tumor angiogenesis

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12 December 2020

10.1023/B:JOMG.0000048773.95897.5F

Identifiers

DOI

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Dimensions Publication ID

11 August 2017

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