(Q40438629)

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Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein

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scholarly article

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Europe PubMed Central

PubMed publication ID

20 September 2017

Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

1 reference

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author name string

Nichole Boyer Arnold

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Murray Korc

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

language of work or name

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publication date

4 April 2005

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

280

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

21858-21866

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Transforming growth factor-beta: possible roles in carcinogenesis

1 reference

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21 January 2018

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

New insights into TGF-beta-Smad signalling

1 reference

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21 January 2018

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

1 reference

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21 January 2018

TGF-beta-receptor-mediated signaling

1 reference

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21 January 2018

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Mammalian antiproliferative signals and their targets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Inhibition of cyclin-dependent kinases by p21

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Retinoblastoma protein recruits histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitory role in transforming growth factor-beta-dependent signaling but affects Smad7-dependent transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Control of Smad7 stability by competition between acetylation and ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer

1 reference

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21 January 2018

Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

The ever-increasing complexity of TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Structure and function of phosphoinositide 3-kinases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

TGF-beta-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Checking out the G(2)/M transition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Vascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endothelium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Smad7 differentially regulates transforming growth factor beta-mediated signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Suppression of keratinocyte growth and differentiation by transforming growth factor beta1 involves multiple signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

The role of human papillomaviruses in human cancers

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21 January 2018

Coordinated regulation of life and death by RB.

1 reference

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21 January 2018

Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity

1 reference

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21 January 2018

Mitogenic response to TGF-beta in 3T3-F442A cells

1 reference

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21 January 2018

Positive and negative regulation of D-type cyclin expression in skeletal myoblasts by basic fibroblast growth factor and transforming growth factor beta. A role for cyclin D1 in control of myoblast differentiation

1 reference

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21 January 2018

Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Smad6s regulates plasminogen activator inhibitor-1 through a protein kinase C-beta-dependent up-regulation of transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

2-Methoxyestradiol-induced apoptosis in prostate cancer cells requires Smad7.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Abnormalities of the RB1 and DCC tumor suppressor genes: Uncommon in human pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500583200

21 January 2018

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

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21 January 2018

The genetics of pancreatic cancer.

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M500583200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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