(Q40471993)

English

Marine alkaloid polycarpine and its synthetic derivative dimethylpolycarpine induce apoptosis in JB6 cells through p53- and caspase 3-dependent pathways.

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scholarly article

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Europe PubMed Central

PubMed publication ID

20 September 2017

Marine alkaloid polycarpine and its synthetic derivative dimethylpolycarpine induce apoptosis in JB6 cells through p53- and caspase 3-dependent pathways. (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

2

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Ann M Bode

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20 September 2017

author name string

Sergey N Fedorov

1

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Europe PubMed Central

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20 September 2017

Valentin A Stonik

3

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Europe PubMed Central

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20 September 2017

Irina A Gorshkova

4

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Europe PubMed Central

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20 September 2017

Patricia C Schmid

5

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Europe PubMed Central

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20 September 2017

Oleg S Radchenko

6

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Europe PubMed Central

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20 September 2017

Evgueni V Berdyshev

7

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Europe PubMed Central

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20 September 2017

Zigang Dong

8

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Europe PubMed Central

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20 September 2017

language of work or name

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publication date

1 December 2004

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20 September 2017

Pharmaceutical Research

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Europe PubMed Central

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20 September 2017

21

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Europe PubMed Central

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20 September 2017

12

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Europe PubMed Central

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20 September 2017

2307-2319

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Europe PubMed Central

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20 September 2017

Deficiency of the stress kinase p38alpha results in embryonic lethality: characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells

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https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

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Essential role for caspase-8 in transcription-independent apoptosis triggered by p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53: death star

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-proliferative effects of new staurosporine derivatives isolated from a marine ascidian and its predatory flatworm

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syntheses and biological activities of bis(3-indolyl)thiazoles, analogues of marine bis(indole)alkaloid nortopsentins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Database of p53 gene somatic mutations in human tumors and cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical pathways of caspase activation during apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death by apoptosis and its protective role against disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53, the cellular gatekeeper for growth and division

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis by caffeine is mediated by the p53, Bax, and caspase 3 pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drugs from the deep: marine natural products as drug candidates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

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p53 has a direct apoptogenic role at the mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marine pharmacology in 1999: antitumor and cytotoxic compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biochemistry of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity- and gene expression-based profiling of ecteinascidin Et 743 and phthalascidin Pt 650.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro toxicity of ET-743 and aplidine, two marine-derived antineoplastics, on human bone marrow haematopoietic progenitors. comparison with the clinical results

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of p53 in phenethyl isothiocyanate-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor compounds from tunicates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Jun NH2-terminal kinase-mediated activation of interleukin-1beta converting enzyme/CED-3-like protease during anticancer drug-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p53 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival-signaling pathway as a promising target for cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p53 tumour suppressor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cyclooxygenase-2 by the activated MEKK1 --> SEK1/MKK4 --> p38 mitogen-activated protein kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15648263

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-004-7683-5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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