(Q40473439)

20 September 2017

title

Loss of Rb-E2F repression results in caspase-8-mediated apoptosis through inactivation of focal adhesion kinase. (English)

1 reference

20 September 2017

Jonathan H Lieman

1

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20 September 2017

Lori A Worley

series ordinal

2

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20 September 2017

J William Harbour

series ordinal

3

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20 September 2017

language of work or name

English

0 references

publication date

7 January 2005

1 reference

Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

11

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20 September 2017

page(s)

10484-10490

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Mouse models of cell death

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409371200

21 January 2018

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21 January 2018

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21 January 2018

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Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

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Differential regulation of apoptotic genes by Rb in human versus mouse cells

21 January 2018

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Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

21 January 2018

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

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Direct coupling of the cell cycle and cell death machinery by E2F.

21 January 2018

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p14ARF links the tumour suppressors RB and p53.

21 January 2018

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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

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E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

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Target gene specificity of E2F and pocket protein family members in living cells

21 January 2018

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Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

21 January 2018

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Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway

21 January 2018

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Bis(N,N-dimethylhydroxamido)hydroxooxovanadate inhibition of protein tyrosine phosphatase activity in intact cells: comparison with vanadate

21 January 2018

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21 January 2018

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Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb.

21 January 2018

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Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

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The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

21 January 2018

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21 January 2018

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Immunofluorescent detection of activation of initiator caspases-8 and -9 during pharmacologically induced apoptosis of cultured HeLa and endothelial cells

21 January 2018

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis

21 January 2018

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Autonomous expression of a noncatalytic domain of the focal adhesion-associated protein tyrosine kinase pp125FAK

21 January 2018

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The focal adhesion targeting sequence is the major inhibitory moiety of Fak-related non-kinase

21 January 2018

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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

21 January 2018

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Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligand

21 January 2018

1 reference

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Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases

21 January 2018

1 reference

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

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Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein

21 January 2018

1 reference

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Epidermal growth factor receptor-dependent, NF-kappaB-independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes

21 January 2018

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Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

21 January 2018

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Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo

21 January 2018

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Expression of protein tyrosine phosphatases and its significance in esophageal cancer

21 January 2018

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The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism

21 January 2018

1 reference

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Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

21 January 2018

1 reference

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Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation

21 January 2018

1 reference

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Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409371200

Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites

21 January 2018

1 reference

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Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409371200

Computer-assisted identification of cell cycle-related genes: new targets for E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409371200

21 January 2018

Identifiers

DOI

10.1074/JBC.M409371200

1 reference

release_3anthpzsrbhnpblpxk2wt6oxry

20 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3anthpzsrbhnpblpxk2wt6oxry

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference