(Q40476423)

20 September 2017

title

Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member. (English)

1 reference

20 September 2017

0 references

1 reference

Leena Heiska

1

1 reference

20 September 2017

Olli Carpén

series ordinal

2

1 reference

20 September 2017

language of work or name

English

0 references

publication date

28 December 2004

1 reference

Journal of Biological Chemistry

20 September 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

20 September 2017

volume

280

1 reference

20 September 2017

issue

11

1 reference

20 September 2017

page(s)

10244-10252

1 reference

Cellular functions regulated by Src family kinases

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Src family tyrosine kinases and growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

v-Src's hold over actin and cell adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

ERM proteins and merlin: integrators at the cell cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Cortical actin organization: lessons from ERM (ezrin/radixin/moesin) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

ERM proteins in cell adhesion and membrane dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin is a substrate for Lck in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Identification and genetic analysis of human and mouse activated Cdc42 interacting protein-4 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Activation of the PKB/AKT pathway by ICAM-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Co-operative effect of c-Src and ezrin in deregulation of cell-cell contacts and scattering of mammary carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Src family kinases are required for integrin but not PDGFR signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Molecular analysis of the interaction between palladin and alpha-actinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Insights into a Single Rod-like Helix in Activated Radixin Required for Membrane−Cytoskeletal Cross-Linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin oligomers are major cytoskeletal components of placental microvilli: a proposal for their involvement in cortical morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Regulation of cell motility by tyrosine phosphorylated villin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Identification of a functional switch for actin severing by cytoskeletal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Cortactin: coupling membrane dynamics to cortical actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

All in the family: the BTB/POZ, KRAB, and SCAN domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

The kelch repeat superfamily of proteins: propellers of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Drosophila kelch is an oligomeric ring canal actin organizer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Identification of Nd1, a novel murine kelch family protein, involved in stabilization of actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Actinfilin, a brain-specific actin-binding protein in postsynaptic density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Characterization of Mayven, a novel actin-binding protein predominantly expressed in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Isolation and characterization of IPP, a novel human gene encoding an actin-binding, kelch-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Sequence and domain organization of scruin, an actin-cross-linking protein in the acrosomal process of Limulus sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Molecular nature of calicin, a major basic protein of the mammalian sperm head cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Role of Src expression and activation in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Src family kinases in tumor progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Ezrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411353200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411353200

1 reference

20 September 2017

1 reference