(Q40504955)

21 September 2017

p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells (English)

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21 September 2017

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14

Paul G Richardson

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21 September 2017

16

Kenneth C Anderson

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Nikhil C Munshi

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Noopur Raje

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3

Dharminder Chauhan

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Kenji Ishitsuka

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1

Teru Hideshima

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Makoto Hamasaki

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21 September 2017

9

Hiromasa Hideshima

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21 September 2017

2

Klaus Podar

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21 September 2017

Constantine S Mitsiades

5

object named as

Constantine Mitsiades

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21 September 2017

11

Aaron N Nguyen

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21 September 2017

Yu-Tzu Tai

6

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21 September 2017

George Schreiner

10

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Tony Navas

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Linda S Higgins

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21 September 2017

language of work or name

English

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publication date

1 November 2004

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21 September 2017

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23

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8766-8776

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21 September 2017

54

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208118

21 September 2017

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cites work

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Mechanisms of clinically relevant drug interactions associated with tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Heat shock proteins--modulators of apoptosis in tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Molecular mechanisms of novel therapeutic approaches for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

The role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Biologic sequelae of c-Jun NH(2)-terminal kinase (JNK) activation in multiple myeloma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Interleukin-6 induces tyrosine phosphorylation of the Ras activating protein Shc, and its complex formation with Grb2 in the human multiple myeloma cell line LP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

PRAK, a novel protein kinase regulated by the p38 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Platelet-collagen interaction: is GPVI the central receptor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

A phase 2 study of bortezomib in relapsed, refractory myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Expression of MDR1/P-glycoprotein, the multidrug resistance protein MRP, and the lung-resistance protein LRP in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Heat-shock proteins as death determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

inferred from DOI database lookup

7 January 2021

based on heuristic

p53-dependent induction of apoptosis by proteasome inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208118

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1208118

1 reference

Dimensions Publication ID

21 September 2017

0 references

1 reference