(Q40508316)

21 September 2017

title

The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism (English)

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21 September 2017

vaccinia virus

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Sandra Blanco

3

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Francisco M Vega

object named as

Francisco M Vega

2

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Pedro A. Lazo

object named as

Pedro A Lazo

5

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author name string

Cláudio R Santos

1

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21 September 2017

Ramiro Barcia

4

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21 September 2017

language of work or name

English

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publication date

1 October 2004

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21 September 2017

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21 September 2017

volume

328

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21 September 2017

issue

2

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21 September 2017

page(s)

254-265

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Stress signals utilize multiple pathways to stabilize p53

21 September 2017

cites work

1 reference

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Identification of sites phosphorylated by the vaccinia virus B1R kinase in viral protein H5R

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Regulation of ubiquitination and degradation of p53 in unstressed cells through C-terminal phosphorylation

7 January 2021

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The ubiquitin ligase COP1 is a critical negative regulator of p53

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Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

7 January 2021

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Expression of vaccinia E3L and K3L genes by a novel recombinant canarypox HIV vaccine vector enhances HIV-1 pseudovirion production and inhibits apoptosis in human cells

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Microarray analysis reveals characteristic changes of host cell gene expression in response to attenuated modified vaccinia virus Ankara infection of human HeLa cells.

7 January 2021

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Mdm-2 binding and TAF(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21.

7 January 2021

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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

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7 January 2021

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7 January 2021

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Characterization of three paralogous members of the Mammalian vaccinia related kinase family

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK

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7 January 2021

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7 January 2021

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DNA damage induces phosphorylation of the amino terminus of p53

7 January 2021

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The role of the E6-p53 interaction in the molecular pathogenesis of HPV.

7 January 2021

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7 January 2021

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Infection with vaccinia virus alters regulation of cell cycle progression

7 January 2021

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Inhibition of p53 degradation by Mdm2 acetylation

7 January 2021

1 reference

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Vaccinia virus infection disarms the mitochondrion-mediated pathway of the apoptotic cascade by modulating the permeability transition pore

7 January 2021

1 reference

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Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis

7 January 2021

1 reference

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E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.08.013

Vaccinia virus gene H5R encodes a protein that is phosphorylated by the multisubstrate vaccinia virus B1R protein kinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.08.013

Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.08.013

inferred from DOI database lookup

7 January 2021

based on heuristic

The vaccinia virus B1R gene product is a serine/threonine protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.08.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Vaccinia virus B1 kinase: phenotypic analysis of temperature-sensitive mutants and enzymatic characterization of recombinant proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2004.08.013

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIROL.2004.08.013

1 reference

21 September 2017

1 reference