(Q40514026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Increased constitutive activity of PKB/Akt in tamoxifen resistant breast cancer MCF-7 cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Nicola J Jordan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Denise Barrow

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Alan E Wakeling

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Robert I Nicholson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

1 September 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

Breast Cancer Research and Treatment

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

167-180

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377841%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1023/b:brea.0000041623.21338.47

1 January 2020

exact match

0 references

cites work

Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

Changes in epidermal growth factor receptor expression and response to ligand associated with acquired tamoxifen resistance or oestrogen independence in the ZR-75-1 human breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Inhibition of protein kinase B/Akt. implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Unravelling the activation mechanisms of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Akt kinases in breast cancer and the results of adjuvant therapy

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Heregulin regulation of Akt/protein kinase B in breast cancer cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

1 reference

7 January 2021

Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex).

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

A multidrug-resistant MCF-7 human breast cancer cell line which exhibits cross-resistance to antiestrogens and hormone-independent tumor growth in vivo.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Epidermal growth factor receptor expression in breast cancer: association with response to endocrine therapy.

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Epidermal growth factor receptor expression as a prognostic indicator in breast cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

The antiepidermal growth factor receptor agent gefitinib (ZD1839/Iressa) improves antihormone response and prevents development of resistance in breast cancer in vitro

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition by gefitinib ('Iressa', ZD1839).

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Nonendocrine pathways and endocrine resistance: observations with antiestrogens and signal transduction inhibitors in combination

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

The ErbB signaling network: receptor heterodimerization in development and cancer

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021

Specific Requirement for the p85-p110α Phosphatidylinositol 3-Kinase during Epidermal Growth Factor-stimulated Actin Nucleation in Breast Cancer Cells

1 reference

https://api.crossref.org/works/10.1023%2FB%3ABREA.0000041623.21338.47

7 January 2021