(Q40583437)

English

Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells.

scientific article published on June 2004

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Baculoviruses expressing the human familial Alzheimer's disease presenilin 1 mutation lacking exon 9 increase levels of an amyloid beta-like protein in Sf9 cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Alzheimer's disease

0 references

Giuseppe Verdile

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Peter Henry St George-Hyslop

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Peter R Schofield

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

author name string

Groth D

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Mathews PM

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Fraser PE

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Ramabhadran TV

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Carter T

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Gandy S

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

language of work or name

0 references

publication date

1 June 2004

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

Molecular Psychiatry

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

594-602

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.mp.4001458

0 references

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Reconstitution of gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Alzheimer beta/A4-amyloid precursor protein: evidence for putative amyloidogenic fragment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Generation of Alzheimer amyloid beta peptide through nonspecific proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Complex N-glycosylated form of nicastrin is stabilized and selectively bound to presenilin fragments.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Expression of human Alzheimer amyloid precursor protein in insect cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Immunolocalization of Alzheimer ?-amyloid peptide precursor to cellular membranes in baculovirus expression system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Baculovirus-infected cells do not produce the amyloid peptide of Alzheimer's disease from its precursor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Isolation and characterization of Drosophila presenilin homolog.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

The biological and pathological function of the presenilin-1 Deltaexon 9 mutation is independent of its defect to undergo proteolytic processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Increased A beta 42(43)-plaque deposition in early-onset familial Alzheimer's disease brains with the deletion of exon 9 and the missense point mutation (H163R) in the PS-1 gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

The role of presenilin-1 in the gamma-secretase cleavage of the amyloid precursor protein of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Drosophila nicastrin is essential for the intramembranous cleavage of notch

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

21 January 2018

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

7 January 2021

based on heuristic

inferred from DOI database lookup

Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001458

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.MP.4001458

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14993906%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40583437&oldid=1498638360"