(Q40583820)

English

Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals

scientific article published on March 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Donglei Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Menashe Bar-Eli

2

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Sylvain Meloche

3

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Pnina Brodt

4

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

language of work or name

0 references

publication date

1 March 2004

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Europe PubMed Central

PubMed publication ID

21 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 September 2017

279

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

19683-19690

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Matrix metalloproteinases in tumor invasion

1 reference

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21 January 2018

Matrix metalloproteinases: a tail of a frog that became a prince

1 reference

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21 January 2018

Extracellular matrix-driven matrix metalloproteinase production in endothelial cells: implications for angiogenesis

1 reference

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Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2.

1 reference

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21 January 2018

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

1 reference

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21 January 2018

Resistance of malignant trophoblast cells to both the anti-proliferative and anti-invasive effects of transforming growth factor-beta.

1 reference

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21 January 2018

Role of phospholipase D in laminin-induced production of gelatinase A (MMP-2) in metastatic cells

1 reference

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21 January 2018

Role of the alpha v beta 3 integrin in human melanoma cell invasion

1 reference

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The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.

1 reference

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21 January 2018

Inhibition of the type I insulin-like growth factor receptor expression and signaling: novel strategies for antimetastatic therapy

1 reference

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21 January 2018

Controlling IGF-receptor function: a possible strategy for tumor therapy

1 reference

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21 January 2018

Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology

1 reference

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21 January 2018

Variation among cell types in the signaling pathways by which IGF-I stimulates specific cellular responses

1 reference

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21 January 2018

The Hallmarks of Cancer

1 reference

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21 January 2018

Molecular crosstalk between p70S6k and MAPK cell signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Regulation of Raf-Akt Cross-talk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

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21 January 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

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21 January 2018

PTEN expression causes feedback upregulation of insulin receptor substrate 2

1 reference

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Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

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21 January 2018

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

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Macrophage cathepsin L, a factor in the erosion of subchondral bone in rheumatoid arthritis

1 reference

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21 January 2018

Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Negative regulation of the serine/threonine kinase B-Raf by Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

1 reference

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21 January 2018

Adaptations of the IGF system during malignancy: human skeletal muscle versus the systemic environment.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

The Akt kinase signals directly to endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Effect of inhibitors of signal transduction on IGF-1-induced protein synthesis associated with hypertrophy in cultured neonatal rat ventricular myocytes

1 reference

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21 January 2018

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

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21 January 2018

Regulation of survival and death of mesangial cells by extracellular matrix.

1 reference

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21 January 2018

The ets protein PEA3 suppresses HER-2/neu overexpression and inhibits tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Transcriptional activation of the porcine P450 11A insulin-like growth factor response element in MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313145200

21 January 2018

Insulin regulation of gene expression through the forkhead transcription factor Foxo1 (Fkhr) requires kinases distinct from Akt.

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M313145200

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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