(Q40595329)

21 September 2017

title

UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy (English)

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21 September 2017

1 reference

L Hu

1

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21 September 2017

X Li

2

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21 September 2017

Q Liu

3

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21 September 2017

J Xu

4

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21 September 2017

H Ge

5

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21 September 2017

Z Wang

6

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21 September 2017

H Wang

7

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21 September 2017

Z Wang

8

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21 September 2017

C Shi

9

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21 September 2017

X Xu

10

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21 September 2017

J Huang

11

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21 September 2017

Z Lin

12

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21 September 2017

R O Pieper

13

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21 September 2017

C Weng

14

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21 September 2017

language of work or name

English

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publication date

5 September 2016

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21 September 2017

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21 September 2017

volume

36

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21 September 2017

issue

8

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21 September 2017

page(s)

1145-1156

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https://scigraph.springernature.com/pub.10.1038/onc.2016.281

21 September 2017

exact match

0 references

cites work

Advances in the genetics of glioblastoma: are we reaching critical mass?

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

The predictive role of E2-EPF ubiquitin carrier protein in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Deregulation of E2-EPF ubiquitin carrier protein in papillary renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

The ubiquitin-conjugating enzyme E2-EPF is overexpressed in primary breast cancer and modulates sensitivity to topoisomerase II inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Recent advances in the protein kinase B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

AKT/PKB signaling: navigating downstream

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

DNA-PK: a dynamic enzyme in a versatile DSB repair pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Inhibition of phosphatidylinositol-3-OH kinase/Akt signaling impairs DNA repair in glioblastoma cells following ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Phosphoprotein analysis using antibodies broadly reactive against phosphorylated motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

DNA end joining becomes less efficient and more error-prone during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Suppression of tumor growth through disruption of hypoxia-inducible transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Akt activation emulates Chk1 inhibition and Bcl2 overexpression and abrogates G2 cell cycle checkpoint by inhibiting BRCA1 foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

The clinical impact of deficiency in DNA non-homologous end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

DNA damage response and growth factor signaling pathways in gliomagenesis and therapeutic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Activation of phosphoinositide 3-kinase by the NBS1 DNA repair protein through a novel activation motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Characterization of a novel keratinocyte ubiquitin carrier protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

The ubiquitin-conjugating enzyme E2-EPF is overexpressed in cervical cancer and associates with tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Expression of hypoxia-inducible factor 1? in brain tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.281

Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27593939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA double strand break repair via non-homologous end-joining

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27593939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2016.281

1 reference

Dimensions Publication ID

21 September 2017

1012160507

0 references

1 reference