(Q40601208)

21 September 2017

title

5-Fluorocytosine increases the toxicity of Wnt-targeting replicating adenoviruses that express cytosine deaminase as a late gene (English)

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21 September 2017

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Fuerer C

1

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21 September 2017

Iggo R

series ordinal

2

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21 September 2017

language of work or name

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1 January 2004

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21 September 2017

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21 September 2017

volume

11

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21 September 2017

issue

2

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21 September 2017

page(s)

142-151

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302148

21 September 2017

exact match

0 references

cites work

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

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Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

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Adenoviruses with Tcf binding sites in multiple early promoters show enhanced selectivity for tumour cells with constitutive activation of the wnt signalling pathway

21 January 2018

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Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization

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Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.

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Gene delivery from the E3 region of replicating human adenovirus: evaluation of the E3B region

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Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

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inferred from DOI database lookup

7 January 2021

based on heuristic

Late expression of p53 from a replicating adenovirus improves tumor cell killing and is more tumor cell specific than expression of the adenoviral death protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302148

inferred from DOI database lookup

7 January 2021

based on heuristic

Monoclonal antibodies which recognize native and denatured forms of the adenovirus DNA-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302148

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302148

1 reference

Dimensions Publication ID

21 September 2017

1014764495

0 references

1 reference