(Q40607325)

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Transforming growth factor-beta1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells

scientific article published on 15 December 2003

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1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Transforming growth factor-beta1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

1 reference

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Hiroshi Kobayashi

2

object named as

Hiroshi Kobayashi

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Yoshiko Tanaka

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Mika Suzuki

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Naohiro Kanayama

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Toshihiko Terao

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

15 December 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

22 September 2017

279

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Europe PubMed Central

PubMed publication ID

22 September 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

8567-8576

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Transforming Growth Factor-β1 Produced by Ovarian Cancer Cell Line HRA Stimulates Attachment and Invasion through an Up-regulation of Plasminogen Activator Inhibitor Type-1 in Human Peritoneal Mesothelial Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumours

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Involvement of cell-cell interactions in the rapid stimulation of Cas tyrosine phosphorylation and Src kinase activity by transforming growth factor-beta 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Src/ERK but not phospholipase D is involved in keratinocyte growth factor-stimulated secretion of matrix metalloprotease-9 and urokinase-type plasminogen activator in SNU-16 human stomach cancer cell

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Oncogenes as inducers of tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

TGF-beta and the Smad signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

TGF-beta signaling by Smad proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Structure, regulation and function of phosphoinositide 3-kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cell line by overexpression of bikunin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Kunitz-type protease inhibitor bikunin disrupts phorbol ester-induced oligomerization of CD44 variant isoforms containing epitope v9 and subsequently suppresses expression of urokinase-type plasminogen activator in human chondrosarcoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Signal transduction pathways involved in rheumatoid arthritis synovial fibroblast interleukin-18-induced vascular cell adhesion molecule-1 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Suppression of urokinase expression and invasiveness by urinary trypsin inhibitor is mediated through inhibition of protein kinase C- and MEK/ERK/c-Jun-dependent signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

A bifunctional hybrid molecule of the amino-terminal fragment of urokinase and domain II of bikunin efficiently inhibits tumor cell invasion and metastasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Role of MAP kinase in tumor progression and invasion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Up-regulation of urokinase-type plasminogen activator and its receptor correlates with enhanced invasion activity of human glioma cells mediated by transforming growth factor-alpha or basic fibroblast growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Oncogenes and signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Using structure to define the function of phosphoinositide 3‐kinase family members

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Bikunin target genes in ovarian cancer cells identified by microarray analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Transforming growth factor-beta1-induced degradation of activated Src tyrosine kinase in rat fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Regulation of transcription by MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309131200

21 January 2018

Identifiers

10.1074/JBC.M309131200

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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