(Q40612327)

22 September 2017

title

A comparison of the properties of a Bcl-xL variant to the wild-type anti-apoptosis inhibitor in mammalian cell cultures (English)

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22 September 2017

5

Michael J Betenbaugh

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22 September 2017

Bruno Figueroa

1

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22 September 2017

T M Sauerwald

series ordinal

2

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22 September 2017

G A Oyler

series ordinal

3

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22 September 2017

J Marie Hardwick

series ordinal

4

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22 September 2017

publication date

1 October 2003

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22 September 2017

published in

Metabolic Engineering

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22 September 2017

volume

5

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22 September 2017

issue

4

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22 September 2017

page(s)

230-245

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The super anti-apoptotic factor Bcl-xFNK constructed by disturbing intramolecular polar interactions in rat Bcl-xL.

22 September 2017

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Diminished cell proliferation associated with the death-protective activity of Bcl-2

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Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

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Protein kinase C: a worthwhile target for anticancer drugs?

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Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

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Protection of hybridoma cells against apoptosis by a loop domain-deficient Bcl-xL protein.

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Conversion of Bcl-2 to a Bax-like death effector by caspases

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7 January 2021

Modulation of cell death by Bcl-XL through caspase interaction

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Primers for mitochondrial DNA replication generated by endonuclease G.

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Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage

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7 January 2021

Apoptosis regulation and its applications to biotechnology

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Cooperative interaction between c-myc and bcl-2 proto-oncogenes

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7 January 2021

Effect of bcl-2 expression on hybridoma cell growth in serum-supplemented, protein-free and diluted media

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7 January 2021

Comparison of Bcl-2 to a Bcl-2 deletion mutant for mammalian cells exposed to culture insults

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7 January 2021

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7 January 2021

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

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7 January 2021

Regulated overexpression of the survival factor bcl-2 in CHO cells increases viable cell density in batch culture and decreases DNA release in extended fixed-bed cultivation

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7 January 2021

Molecular regulation of cell-cycle progression and apoptosis in mammalian cells: implications for biotechnology

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Apoptosis in batch cultures of Chinese hamster ovary cells

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7 January 2021

Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.

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Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

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7 January 2021

Inducible expression of Bcl-XL restricts apoptosis resistance to the antibody secretion phase in hybridoma cultures

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7 January 2021

Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c

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7 January 2021

Deciphering the apoptotic pathway: all roads lead to death

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7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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7 January 2021

Part II. Overexpression of bcl-2 family members enhances survival of mammalian cells in response to various culture insults.

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7 January 2021

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

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7 January 2021

Impact of coexpression and coamplification of sICAM and antiapoptosis determinants bcl-2/bcl-x(L) on productivity, cell survival, and mitochondria number in CHO-DG44 grown in suspension and serum-free media.

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7 January 2021

Apoptosis-resistant NS/0 E1B-19K myelomas exhibit increased viability and chimeric antibody productivity under cell cycle modulating conditions

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7 January 2021

Apoptosis-resistant E1B-19K-expressing NS/0 myeloma cells exhibit increased viability and chimeric antibody productivity under perfusion culture conditions.

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7 January 2021

Dose-dependent reduction of apoptosis in nutrient-limited cultures of NS/0 myeloma cells transfected with the E1B-19K adenoviral gene.

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7 January 2021

Sindbis virus induces apoptosis through a caspase-dependent, CrmA-sensitive pathway.

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7 January 2021

Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells

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7 January 2021

Bcl-2 over-expression reduces growth rate and prolongs G1 phase in continuous chemostat cultures of hybridoma cells

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7 January 2021

Enhancement of survivability of mammalian cells by overexpression of the apoptosis-suppressor gene bcl-2.

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7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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7 January 2021

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7 January 2021

Bcl-2 mediated suppression of apoptosis in myeloma NS0 cultures.

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7 January 2021

Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.

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7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

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7 January 2021

Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival

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7 January 2021

Growth factors can influence cell growth and survival through effects on glucose metabolism

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7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

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7 January 2021

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Identifiers

DOI

1 reference

22 September 2017

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