(Q40612662)

22 September 2017

A comprehensive assessment of p53-responsive genes following adenoviral-p53 gene transfer in Bcl-2-expressing prostate cancer cells (English)

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22 September 2017

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2

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22 September 2017

Kevin B Spurgers

1

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22 September 2017

Raymond E Meyn

3

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22 September 2017

David L Gold

4

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22 September 2017

Christopher J Logothetis

5

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22 September 2017

Terry J Johnson

6

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22 September 2017

Timothy J McDonnell

7

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22 September 2017

language of work or name

English

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publication date

1 March 2004

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22 September 2017

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22 September 2017

23

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22 September 2017

9

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22 September 2017

1712-1723

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207293

22 September 2017

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cites work

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Inhibition of p53 transcriptional activity by Bcl-2 requires its membrane-anchoring domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

The p53MH algorithm and its application in detecting p53-responsive genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Covalent and noncovalent modifiers of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer can have important prognostic value

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical results

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

The p53 and Mdm2 families in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Clinical update of Ad-p53 gene therapy for lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

The 26S proteasome: subunits and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Bcl-2 expression causes redistribution of glutathione to the nucleus

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Redox aspects of Bcl-2 function.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

The Bcl-2 protein family: arbiters of cell survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

BCL-2 is involved in preventing oxidant-induced cell death and in decreasing oxygen radical production.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Mammalian G1- and S-phase checkpoints in response to DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Bcl-2 inhibits p53 nuclear import following DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Bcl-2 accelerates multistep prostate carcinogenesis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

p53 oncogene mutations in three human prostate cancer cell lines

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Down-regulation of survivin by antisense oligonucleotides increases apoptosis, inhibits cytokinesis and anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Bcl-2 family members inhibit oxidative stress-induced programmed cell death in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Essential role for caspase-8 in transcription-independent apoptosis triggered by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Bcl-2 suppresses apoptosis resulting from disruption of the NF-kappa B survival pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Prostate carcinoma cell death resulting from inhibition of proteasome activity is independent of functional Bcl-2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

p53 mutations in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Superoxide dismutase as a target for the selective killing of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

INGN 201: Ad-p53, Ad5CMV-p53, Adenoviral p53, INGN 101, p53 gene therapy--Introgen, RPR/INGN 201

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Cancer. p53, guardian of the genome

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

The p53 tumour suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Bcl-2-related proteins and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Rapid destruction of human Cdc25A in response to DNA damage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Bcl-2 as a predictor of chemosensitivity and prognosis in primary epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

p53 has a direct apoptogenic role at the mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Resistance to radiation-induced apoptosis in Bcl-2-expressing cells is reversed by depleting cellular thiols

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Angiogenesis, p53, bcl-2 and Ki-67 in the progression of prostate cancer after radical prostatectomy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Role and function of the 26S proteasome in proliferation and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Gene therapy for bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Deletion of the Saccharomyces cerevisiae TRR1 gene encoding thioredoxin reductase inhibits p53-dependent reporter gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Does p53 status influence tumor response to anticancer therapies?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Molecular markers of outcome after radiotherapy in patients with prostate carcinoma: Ki-67, bcl-2, bax, and bcl-x

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Role of cysteine residues in regulation of p53 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Mechanisms of p53-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Molecular determinants of cell death induction following adenovirus-mediated gene transfer of wild-type p53 in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Death and decoy receptors and p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Assessment of p53 gene transfer and biological activities in a clinical study of adenovirus-p53 gene therapy for recurrent ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Safety evaluation of Ad5CMV-p53 in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207293

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207293

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Dimensions Publication ID

22 September 2017

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1 reference