(Q40625711)

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HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates.

scientific article published on 14 October 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14561767%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14561767%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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20 December 2019

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Corinne Besnard-Guerin

1

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20 December 2019

Nadia Belaïdouni

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20 December 2019

Emmanuel Segeral

4

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20 December 2019

Aude Jobart

5

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20 December 2019

Christelle Marchal

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20 December 2019

Richard Benarous

7

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20 December 2019

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14 October 2003

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20 December 2019

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8

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Journal of Biological Chemistry

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20 December 2019

279

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20 December 2019

1

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20 December 2019

788-795

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20 December 2019

Vpu Exerts a Positive Effect on HIV-1 Infectivity by Down-modulating CD4 Receptor Molecules at the Surface of HIV-1-producing Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Negative regulation of axis formation and Wnt signaling in Xenopus embryos by the F-box/WD40 protein beta TrCP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent expression of antiapoptotic factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Differential interaction of plakoglobin and beta-catenin with the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Beta-catenin: a key mediator of Wnt signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

TCF transcription factors, mediators of Wnt-signaling in development and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

ER-associated degradation in protein quality control and cellular regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tailed macaques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Interaction between the Cytoplasmic Domains of HIV-1 Vpu and CD4: Role of Vpu Residues Involved in CD4 Interaction andin VitroCD4 Degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308068200

21 January 2018

Identifiers

10.1074/JBC.M308068200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14561767%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14561767%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

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