(Q40631665)

22 September 2017

title

Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity (English)

1 reference

22 September 2017

Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

14 March 2024

2

Lap Ho

1 reference

22 September 2017

1

Weiping Qin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507922

14 March 2024

Giulio Maria Pasinetti

10

object named as

Giulio Maria Pasinetti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507922

14 March 2024

author name string

Yuanzhen Peng

4

1 reference

22 September 2017

Zhong Zhao

5

1 reference

22 September 2017

Zhongmin Xiang

6

1 reference

22 September 2017

Junichi Shioi

8

1 reference

22 September 2017

Jason Suh

9

1 reference

22 September 2017

Patrick N. Pompl

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507922

14 March 2024

Nikolaos K. Robakis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507922

14 March 2024

language of work or name

English

0 references

publication date

24 September 2003

1 reference

full work available at URL

22 September 2017

http://www.jbc.org/content/278/51/50970.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507922

https://api.elsevier.com/content/article/PII:S0021925820753512?httpAccept=text/xml

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

https://api.elsevier.com/content/article/PII:S0021925820753512?httpAccept=text/plain

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

https://syndication.highwire.org/content/doi/10.1074/jbc.M307699200

14 March 2024

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Journal of Biological Chemistry

14 March 2024

published in

1 reference

22 September 2017

volume

278

1 reference

22 September 2017

issue

51

1 reference

22 September 2017

page(s)

50970-50977

1 reference

Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Nonsteroidal anti-inflammatory drug use and the risk for Alzheimer's disease: dissecting the epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Do NSAIDs prevent Alzheimer's disease? And, if so, why? The epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Double placebo design in a prevention trial for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Clinical trial of indomethacin in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Prostaglandins and other lipid mediators in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Induction of cyclo-oxygenase 2 in brains of patients with Down's syndrome and dementia of Alzheimer type: specific localization in affected neurones and axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Cyclooxygenase-2 in the hippocampus is up-regulated in Alzheimer's disease but not in variant Alzheimer's disease with cotton wool plaques in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Sensitivity and reproducibility in adenoviral infectious titer determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Endogenous EP4 prostaglandin receptors coupled positively to adenylyl cyclase in Chinese hamster ovary cells: pharmacological characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Cyclo-oxygenase inhibitors and Alzheimer's: are we well ADAPTed?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307699200

COX-2 as a multifunctional neuronal modulator

21 January 2018

14

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice.

14 March 2024

26

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Cell-free assays for gamma-secretase activity

14 March 2024

31

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

14 March 2024

38

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Elevated CSF prostaglandin E2 levels in patients with probable AD

14 March 2024

39

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology.

14 March 2024

40

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Prostanoid receptor subtypes

14 March 2024

42

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

14 March 2024

44

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

14 March 2024

45

1 reference

https://api.crossref.org/works/10.1074/JBC.M307699200

14 March 2024

Identifiers

1 reference

22 September 2017

1 reference