(Q40637846)

English

Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm

scientific article published on 3 September 2003

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scholarly article

1 reference

Europe PubMed Central

22 September 2017

Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm (English)

1 reference

Europe PubMed Central

22 September 2017

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author name string

Eddy S Yang

1

1 reference

Europe PubMed Central

22 September 2017

Kerry L Burnstein

2

1 reference

Europe PubMed Central

22 September 2017

language of work or name

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publication date

3 September 2003

1 reference

Europe PubMed Central

22 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

22 September 2017

278

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Europe PubMed Central

22 September 2017

46862-46868

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Europe PubMed Central

22 September 2017

47

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Europe PubMed Central

22 September 2017

Vitamin D: a modulator of cell proliferation and differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Vitamin D receptor content and transcriptional activity do not fully predict antiproliferative effects of vitamin D in human prostate cancer cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 in human prostate cancer cell line LNCaP involves reduction of cyclin-dependent kinase 2 activity and persistent G1 accumulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Vitamin D-mediated growth inhibition of an androgen-ablated LNCaP cell line model of human prostate cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Association of p27Kip1 levels with recurrence and survival in patients with stage C prostate carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Constitutive MEK/MAPK activation leads to p27(Kip1) deregulation and antiestrogen resistance in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Sp1 and NF-Y synergistically mediate the effect of vitamin D(3) in the p27(Kip1) gene promoter that lacks vitamin D response elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Control of cyclin-dependent kinase inhibitor p27 expression by cap-independent translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Cyclin-dependent kinase 2 nucleocytoplasmic translocation is regulated by extracellular regulated kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Calcitriol-induced apoptosis in LNCaP cells is blocked by overexpression of Bcl-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Rapamycin resistance tied to defective regulation of p27Kip1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Cdk2 associates with MAP kinase in vivo and its nuclear translocation is dependent on MAP kinase activation in IL-2-dependent Kit 225 T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Inhibition of proliferation of prostate cancer cells by a 19-nor-hexafluoride vitamin D3 analogue involves the induction of p21waf1, p27kip1 and E-cadherin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Expression of p27/Kip1 is down-regulated in human prostate carcinoma progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Metabolic stabilization of p27 in senescent fibroblasts correlates with reduced expression of the F-box protein Skp2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306340200

21 January 2018

Identifiers

10.1074/JBC.M306340200

1 reference

Europe PubMed Central

22 September 2017

1 reference

Europe PubMed Central

22 September 2017

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