(Q40647950)

22 September 2017

cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis (English)

1 reference

22 September 2017

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4

Gregory J Gores

1 reference

22 September 2017

Annette Grambihler

1

1 reference

22 September 2017

Hajime Higuchi

series ordinal

2

1 reference

22 September 2017

Steven F Bronk

series ordinal

3

1 reference

22 September 2017

language of work or name

English

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publication date

12 May 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

26831-26837

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22 September 2017

29

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Apoptosis and liver disease

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Nitric oxide ameliorates hydrophobic bile acid-induced apoptosis in isolated rat hepatocytes by non-mitochondrial pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Cholestasis increases tumor necrosis factor-related apoptotis-inducing ligand (TRAIL)-R2/DR5 expression and sensitizes the liver to TRAIL-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Signal transduction by tumor necrosis factor mediated by JNK protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

The ups and downs of MEK kinase interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

FADD/MORT1, a signal transducer that can promote cell death or cell growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Casper is a FADD- and caspase-related inducer of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

CASH, a novel caspase homologue with death effector domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Phosphoinositide 3-kinase, but not mitogen-activated protein kinase, pathway is involved in hepatocyte growth factor-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

The primary structure of p38 gamma: a new member of p38 group of MAP kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Effects of a dominant interfering mutant of FADD on signal transduction in activated T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

The role of c-FLIP in modulation of CD95-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Genetic defects in hepatocanalicular transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303229200

21 January 2018

Identifiers

DOI

10.1074/JBC.M303229200

1 reference

22 September 2017

1 reference