(Q40708684)

23 September 2017

Functional role of arginine 373 in substrate translocation by the reduced folate carrier (English)

1 reference

23 September 2017

1 reference

Heather Sadlish

1

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23 September 2017

Frederick M R Williams

series ordinal

2

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23 September 2017

Wayne F Flintoff

series ordinal

3

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23 September 2017

language of work or name

English

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publication date

22 August 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

44

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23 September 2017

42105-42112

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Folic acid: nutritional biochemistry, molecular biology, and role in disease processes

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Down-regulation of reduced folate carrier gene (RFC1) expression after exposure to methotrexate in ZR-75-1 breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Topological and functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Cytoplasmic domains of the reduced folate carrier are essential for trafficking, but not function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter w

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Mutations in the reduced-folate carrier affect protein localization and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Isolation of high-molecular-weight DNA from mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Proximity of periplasmic loops in the lactose permease of Escherichia coli determined by site-directed cross-linking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Helix proximity in OxlT, the oalate:formate antiporter of oxalobacter formigenes. Cross-linking between TM2 and TM11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Functional interactions between arginine-133 and aspartate-88 in the human reduced folate carrier: evidence for a charge-pair association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Transport of methotrexate in Chinese hamster ovary cells: a mutant defective in methotrexate uptake and cell binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Genetic characterization of methotrexate-resistant chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Mutant Chinese hamster ovary cells with defective methotrexate uptake are distinguishable by reversion analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

Chromosomal localization of the reduced folate transporter gene (SLC19A1) in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206459200

21 January 2018

Identifiers

DOI

10.1074/JBC.M206459200

1 reference

23 September 2017

1 reference