(Q40763347)

23 September 2017

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation (English)

1 reference

23 September 2017

Davide Danovi

2

0 references

Jean-Christophe Marine

object named as

Jean-Christophe Marine

series ordinal

6

0 references

Emanuela Colombo

series ordinal

3

object named as

Emanuela Colombo

1 reference

23 September 2017

1

Domenico Migliorini

1 reference

23 September 2017

Roberta Carbone

4

1 reference

PubMed ID

11744695

23 September 2017

Pier Giuseppe Pelicci

series ordinal

5

1 reference

PubMed ID

11744695

23 September 2017

language of work or name

English

0 references

publication date

13 December 2001

1 reference

Journal of Biological Chemistry

23 September 2017

1 reference

23 September 2017

277

1 reference

23 September 2017

7318-7323

1 reference

23 September 2017

9

1 reference

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Isolation and identification of the human homolog of a new p53-binding protein, Mdmx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

MdmX protects p53 from Mdm2-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

MDM2 interacts with MDMX through their RING finger domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

A novel MDMX transcript expressed in a variety of transformed cell lines encodes a truncated protein with potent p53 repressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

MDM2 and MDMX can interact differently with ARF and members of the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108795200

21 January 2018

Identifiers

DOI

10.1074/JBC.M108795200

1 reference

23 September 2017

1 reference

PubMed ID

11744695