(Q40788169)

23 September 2017

p63 controls cell migration and invasion by transcriptional regulation of MTSS1. (English)

1 reference

23 September 2017

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

A Giacobbe

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

M Compagnone

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

L Bongiorno-Borbone

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

A Antonov

4

1 reference

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14 June 2020

E K Markert

5

1 reference

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14 June 2020

J H Zhou

6

1 reference

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14 June 2020

M Annicchiarico-Petruzzelli

7

1 reference

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14 June 2020

G Melino

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

language of work or name

English

0 references

publication date

29 June 2015

1 reference

23 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26119942%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

issue

12

1 reference

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14 June 2020

page(s)

1602-1608

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2015.230

14 June 2020

exact match

0 references

cites work

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

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P63 and P73: P53 mimics, menaces and more

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The p53 family: guardians of maternal reproduction.

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p63 regulates glutaminase 2 expression.

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The roles of p63 in cancer

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TAp63 and DeltaNp63 in cancer and epidermal development

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TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

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p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

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p63 transcriptional regulation of epithelial integrity and cancer

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How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors

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p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.

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TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

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FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

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Crosstalk among p53 family members in cutaneous carcinoma.

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p63 expression in normal, hyperplastic and malignant breast tissues

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p63, a p53 homologue, is a selective nuclear marker of myoepithelial cells of the human breast

21 January 2018

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p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling

21 January 2018

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Overexpression of ΔNp63α induces a stem cell phenotype in MCF7 breast carcinoma cell line through the Notch pathway

21 January 2018

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ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling

21 January 2018

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Collective invasion in breast cancer requires a conserved basal epithelial program

21 January 2018

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MIM: a multifunctional scaffold protein

21 January 2018

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p63 regulates proliferation and differentiation of developmentally mature keratinocytes

21 January 2018

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MTSS1: a multifunctional protein and its role in cancer invasion and metastasis

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Metastasis suppressor 1 (MTSS1) demonstrates prognostic value and anti-metastatic properties in breast cancer

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MIM, a potential metastasis suppressor gene in bladder cancer

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MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma

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EGF induces microRNAs that target suppressors of cell migration: miR-15b targets MTSS1 in breast cancer

21 January 2018

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Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells

21 January 2018

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The impact of Metastasis Suppressor-1, MTSS1, on oesophageal squamous cell carcinoma and its clinical significance.

21 January 2018

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MTSS1 is a metastasis driver in a subset of human melanomas

21 January 2018

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Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism

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Involvement of Rac in actin cytoskeleton rearrangements induced by MIM-B.

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The cofilin pathway in breast cancer invasion and metastasis

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ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

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Loss of DeltaNp63alpha promotes invasion of urothelial carcinomas via N-cadherin/Src homology and collagen/extracellular signal-regulated kinase pathway.

21 January 2018

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Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

21 January 2018

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ΔNp63 transcriptionally regulates brachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis

21 January 2018

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p63-Mediated activation of the β-catenin/c-Myc signaling pathway stimulates esophageal squamous carcinoma cell invasion and metastasis

21 January 2018

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ΔNp63 versatilely regulates a Broad NF-κB gene program and promotes squamous epithelial proliferation, migration, and inflammation

21 January 2018

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p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis.

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GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation

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The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26119942