(Q40796996)

23 September 2017

Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells (English)

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23 September 2017

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3

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23 September 2017

Frost V

1

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23 September 2017

Al-Mehairi S

series ordinal

2

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23 September 2017

language of work or name

English

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publication date

1 May 2001

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23 September 2017

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23 September 2017

20

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23 September 2017

2737-2748

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23 September 2017

22

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204367

23 September 2017

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cites work

Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Involvement of caspase-1 and caspase-3 in the production and processing of mature human interleukin 18 in monocytic THP.1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Antiproliferative function of p27kip1 is frequently inhibited in highly malignant Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cell cycle arrest following exposure of EBV-immortalised B-cells to gamma irradiation correlates with inhibition of cdk2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Proteolytic cleavage of the mdm2 oncoprotein during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Production by EBV infection of an EBNA-positive subline from an EBNA-negative human lymphoma cell line without detectable EBV DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

A recombinant adenovirus expressing p27Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Inhibition of human caspases by peptide-based and macromolecular inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Caspase-dependent Cdk activity is a requisite effector of apoptotic death events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Caspase activation is required for T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Characterization of the murine cyclin-dependent kinase inhibitor gene p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Rapamycin resistance tied to defective regulation of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Control of pRB phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Activation of an MDM2-specific caspase by p53 in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Caspase activation without death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Processing and activation of pro-interleukin-16 by caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Evidence for CPP32 activation in the absence of apoptosis during T lymphocyte stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Substrate specificities of caspase family proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

p27Kip1 overexpression causes apoptotic death of mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Activation of caspase-3-like enzymes in non-apoptotic T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204367

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204367

1 reference

Dimensions Publication ID

23 September 2017

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1 reference