(Q40833596)

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Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint

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scholarly article

1 reference

Europe PubMed Central

24 September 2017

Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint (English)

1 reference

Europe PubMed Central

24 September 2017

neuroectodermal tumor

1 reference

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inferred from title

Mikhail Blagosklonny

9

object named as

Blagosklonny MV

1 reference

Europe PubMed Central

24 September 2017

12

object named as

Trepel JB

1 reference

Europe PubMed Central

24 September 2017

Theodor W Schulte

7

object named as

Schulte TW

1 reference

Europe PubMed Central

24 September 2017

author name string

Kim JS

1

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Europe PubMed Central

24 September 2017

Pirnia F

2

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Europe PubMed Central

24 September 2017

Choi YH

3

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Europe PubMed Central

24 September 2017

Nguyen PM

4

1 reference

Europe PubMed Central

24 September 2017

Knepper B

5

1 reference

Europe PubMed Central

24 September 2017

Tsokos M

6

1 reference

Europe PubMed Central

24 September 2017

Birrer MJ

8

1 reference

Europe PubMed Central

24 September 2017

Schaefer O

10

1 reference

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24 September 2017

Mushinski JF

11

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24 September 2017

language of work or name

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publication date

1 December 2000

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24 September 2017

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Europe PubMed Central

24 September 2017

19

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24 September 2017

52

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24 September 2017

6082-6090

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Europe PubMed Central

24 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204008

0 references

DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma

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Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP

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Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs

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Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

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Distinct roles for E2F proteins in cell growth control and apoptosis

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Gene rearrangements in Ewing's sarcoma

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The regulation of E2F by pRB-family proteins

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

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A cell cycle-regulated inhibitor of cyclin-dependent kinases

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Simple procedure of DNA isolation from human serum

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Cell cycle-specific effects of lovastatin

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Progress in the molecular biology of ewing tumors.

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Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells

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Suppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

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21 January 2018

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

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The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve.

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Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

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E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

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Genetic determinants of p53-induced apoptosis and growth arrest

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

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Clinical outcomes in statin treatment trials: a meta-analysis

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Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis

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Anticancer drug targets: cell cycle and checkpoint control.

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Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells

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Episome-generated N-myc antisense RNA restricts the differentiation potential of primitive neuroectodermal cell lines

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

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E2F-1 functions in mice to promote apoptosis and suppress proliferation

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Factors associated with tumor volume and primary metastases in Ewing tumors: results from the (EI)CESS studies

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Posttranslational regulation of the retinoblastoma gene family member p107 by calpain protease

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Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

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Lovastatin-induced apoptosis of human medulloblastoma cell lines in vitro

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Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis

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Tumor induction and tissue atrophy in mice lacking E2F-1

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7 January 2021

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10.1038/SJ.ONC.1204008

1 reference

Europe PubMed Central

24 September 2017

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1 reference

Europe PubMed Central

24 September 2017

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