(Q40851487)

24 September 2017

title

Pharmacokinetics of morphine-6-glucuronide and its formation from morphine after intravenous administration (English)

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24 September 2017

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J Lötsch

1

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author name string

M Weiss

series ordinal

2

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24 September 2017

G Kobal

series ordinal

3

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24 September 2017

G Geisslinger

series ordinal

4

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24 September 2017

language of work or name

English

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publication date

1 June 1998

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Clinical Pharmacology & Therapeutics

24 September 2017

published in

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24 September 2017

volume

63

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24 September 2017

issue

6

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24 September 2017

page(s)

629-639

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Gene expression in oestrogen-dependent human breast cancer xenograft tumours

24 September 2017

cites work

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The analgesic activity of morphine-6-glucuronide

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Antinociceptive and ventilatory effects of the morphine metabolites: morphine-6-glucuronide and morphine-3-glucuronide

21 January 2018

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Opioid receptor agonist potencies of morphine and morphine-6-glucuronide in the guinea-pig ileum

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Enhanced binding of morphine and nalorphine to opioid delta receptor by glucuronate and sulfate conjugations at the 6-position

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Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: comparison with morphine

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Lack of Analgesic Activity of Morphine-6-glucuronide after Short-term Intravenous Administration in Healthy Volunteers

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Morphine-6-glucuronide might mediate the prolonged opioid effect of morphine in acute renal failure

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Chronic nausea and morphine-6-glucuronide

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Plasma morphine and morphine-6-glucuronide during chronic morphine therapy for cancer pain: plasma profiles, steady-state concentrations and the consequences of renal failure

7 January 2021

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Analysis of morphine and its 3- and 6-glucuronides by high performance liquid chromatography with fluorimetric detection following solid phase extraction from neonatal plasma

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Pharmacokinetics of morphine and its glucuronides after intravenous infusion of morphine and morphine-6-glucuronide in healthy volunteers*

7 January 2021

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Fast reliable assay for morphine and its metabolites using high-performance liquid chromatography and native fluorescence detection

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Determination of pharmacokinetic constants after multiple infusions of drugs.

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Disposition kinetics of lidocaine in normal subjects.

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A general model of metabolite kinetics following intravenous and oral administration of the parent drug

7 January 2021

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7 January 2021

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Prediction of creatinine clearance from serum creatinine

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Morphine pharmacokinetics and metabolism in humans. Enterohepatic cycling and relative contribution of metabolites to active opioid concentrations

7 January 2021

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Disposition of morphine-6-glucuronide and morphine in healthy volunteers

7 January 2021

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Extrahepatic metabolism of morphine occurs in humans

7 January 2021

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Membrane transport as a determinant of the hepatic elimination of drugs and metabolites

7 January 2021

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Oral morphine in cancer pain: influences on morphine and metabolite concentration

7 January 2021

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10.1016/S0009-9236(98)90086-8

7 January 2021

Identifiers

DOI

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24 September 2017

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