(Q40852082)

24 September 2017

title

Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection (English)

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24 September 2017

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18

Gerin JL

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24 September 2017

1

Tennant BC

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24 September 2017

16

Cote PJ

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24 September 2017

Baldwin BH

2

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24 September 2017

Graham LA

3

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24 September 2017

Ascenzi MA

4

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24 September 2017

Hornbuckle WE

5

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24 September 2017

Rowland PH

6

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24 September 2017

Tochkov IA

7

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24 September 2017

Yeager AE

8

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24 September 2017

Erb HN

9

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24 September 2017

Colacino JM

10

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24 September 2017

Lopez C

11

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24 September 2017

Engelhardt JA

12

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24 September 2017

Bowsher RR

13

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24 September 2017

Richardson FC

14

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24 September 2017

Lewis W

15

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24 September 2017

Korba BE

17

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24 September 2017

language of work or name

English

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publication date

1 July 1998

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24 September 2017

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24 September 2017

volume

28

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24 September 2017

issue

1

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24 September 2017

page(s)

179-191

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Activities of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and its metabolites against herpes simplex virus types 1 and 2 in cell culture and in mice infected intracerebrally with herpes simplex virus type 2

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

The in vitro anti-hepatitis B virus activity of FIAU [1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodo)uracil] is selective, reversible, and determined, at least in part, by the host cell

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Fialuridine accumulates in DNA of dogs, monkeys, and rats following long-term oral administration

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Chronic hepatitis and hepatocellular carcinoma associated with persistent woodchuck hepatitis virus infection

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Hepatocarcinogenicity of the woodchuck hepatitis virus

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Hepatocellular carcinoma in woodchuck hepatitis virus-infected woodchucks: presence of viral DNA in tumor tissue from chronic carriers and animals serologically recovered from acute infections

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

New enzyme immunoassays for the serologic detection of woodchuck hepatitis virus infection

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Sensitive and specific radioimmunoassay for fialuridine: initial assessment of pharmacokinetics after single oral doses to healthy volunteers

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Reye's syndrome: current concepts

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Lactic acidosis complicating the acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Fulminant hepatic failure associated with 2',3'-dideoxyinosine (ddI)

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Fulminant hepatitis with severe lactate acidosis in HIV-infected patients on didanosine therapy

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Hepatomegaly with severe steatosis in HIV-seropositive patients

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Reye's syndrome in adult with AIDS

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Mitochondrial toxicity of antiviral drugs

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Effect of fialuridine on replication of mitochondrial DNA in CEM cells and in human hepatoblastoma cells in culture

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Incorporation of fialuridine (FIAU) into mitochondrial DNA and effects of FIAU on the morphology of mitochondria in human hepatoblastoma cells

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Mammalian DNA polymerases alpha, beta, gamma, delta, and epsilon incorporate fialuridine (FIAU) monophosphate into DNA and are inhibited competitively by FIAU Triphosphate

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Kinetic analysis of the interaction between the diphosphate of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, ddCTP, AZTTP, and FIAUTP with human DNA polymerases beta and gamma

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Incorporation of metabolites of 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine into deoxyribonucleic acid of neoplastic and normal mammalian tissues

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Quantitative determination of antiviral nucleoside analog in DNA

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Induction of the mitochondrial permeability transition by protease activity in rats: a mechanism of hepatocyte necrosis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Sodium-mediated cell swelling is associated with irreversible damage in isolated hepatocytes exposed to hypoxia or mitochondrial toxins.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks

1 reference

https://api.crossref.org/works/10.1002%2FHEP.510280124

7 January 2021

Identifiers

DOI

10.1002/HEP.510280124

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24 September 2017

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