(Q41068541)

26 September 2017

EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice (English)

1 reference

regulation of long-chain fatty acid import into cell

26 September 2017

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0140212

negative regulation of long-chain fatty acid import into cell

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0140213

positive regulation of long-chain fatty acid import into cell

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0140214

glutamyl-prolyl-tRNA synthetase 1

1 reference

Ribosomal protein S6 kinase B1

1 reference

Solute carrier family 27 member 1

1 reference

long-chain fatty acid import into cell

1 reference

Solute carrier family 27 (fatty acid transporter), member 1

1 reference

Glutamyl-prolyl-tRNA synthetase

1 reference

Ribosomal protein S6 kinase, polypeptide 1

1 reference

author name string

Abul Arif

1

1 reference

26 September 2017

Fulvia Terenzi

2

1 reference

26 September 2017

Alka A Potdar

3

1 reference

26 September 2017

Jie Jia

4

1 reference

26 September 2017

Jessica Sacks

5

1 reference

26 September 2017

Arnab China

6

1 reference

26 September 2017

Dalia Halawani

7

1 reference

26 September 2017

Kommireddy Vasu

8

1 reference

26 September 2017

Xiaoxia Li

9

1 reference

26 September 2017

J Mark Brown

10

1 reference

26 September 2017

Jie Chen

11

1 reference

26 September 2017

Sara C Kozma

12

1 reference

26 September 2017

George Thomas

13

1 reference

26 September 2017

Paul L Fox

14

1 reference

26 September 2017

language of work or name

English

0 references

publication date

8 February 2017

1 reference

26 September 2017

1 reference

26 September 2017

542

1 reference

26 September 2017

357-361

1 reference

26 September 2017

7641

1 reference

https://scigraph.springernature.com/pub.10.1038/nature21380

26 September 2017

0 references

cites work

S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Adipose fatty acid oxidation is required for thermogenesis and potentiates oxidative stress-induced inflammation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Fatty acid transport protein 1 can compensate for fatty acid transport protein 4 in the developing mouse epidermis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Origin and evolution of glutamyl-prolyl tRNA synthetase WHEP domains reveal evolutionary relationships within Holozoa

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

A Central role for mTOR in lipid homeostasis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

mTOR is a key modulator of ageing and age-related disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophages

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Health Evaluation of Experimental Laboratory Mice

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Organ size control by Hippo and TOR pathways.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Phosphorylation of glutamyl-prolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

T-cadherin is critical for adiponectin-mediated cardioprotection in mice

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

New functions of aminoacyl-tRNA synthetases beyond translation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

S6K1 plays a critical role in early adipocyte differentiation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Extending healthy life span--from yeast to humans

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Two-site phosphorylation of EPRS coordinates multimodal regulation of noncanonical translational control activity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

A novel role for fatty acid transport protein 1 in the regulation of tricarboxylic acid cycle and mitochondrial function in 3T3-L1 adipocytes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Mice deficient in ribosomal protein S6 phosphorylation suffer from muscle weakness that reflects a growth defect and energy deficit

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Molecular mechanisms of mTOR-mediated translational control

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

A post-transcriptional pathway represses monocyte VEGF-A expression and angiogenic activity.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Fatty acid metabolism in adipocytes: functional analysis of fatty acid transport proteins 1 and 4.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Critical nodes in signalling pathways: insights into insulin action

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

A simple method for the isolation and purification of total lipides from animal tissues

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

NAADP mediates insulin-stimulated glucose uptake and insulin sensitization by PPARγ in adipocytes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Real-time quantification of fatty acid uptake using a novel fluorescence assay

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Active baculovirus recombinant p70s6k and p85s6k produced as a function of the infectious response.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Stimulation of cholesteryl ester synthesis in macrophages by extracts of atherosclerotic human aortas and complexes of albumin/cholesteryl esters

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Assay of protein kinases using peptides with basic residues for phosphocellulose binding

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5480610

Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE21380

inferred from DOI database lookup

7 January 2021

based on heuristic

Chromatographic depletion of lipoproteins from plasma and recovery of apolipoproteins

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE21380

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE21380

1 reference

release_4tcqe5l6crhaljwfolmry6kgd4

26 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4tcqe5l6crhaljwfolmry6kgd4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

26 September 2017

1 reference