(Q41069719)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

7

1 reference

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30 March 2020

author name string

Jess-Karan S Dhillon

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Cara Riffe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Brenda D Moore

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Yong Ran

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Paramita Chakrabarty

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Todd E Golde

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

language of work or name

English

0 references

publication date

14 September 2017

1 reference

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30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

e0184731

1 reference

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Creative Commons Attribution 4.0 International

30 March 2020

copyright license

start time

14 September 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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26 September 2017

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26 September 2017

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Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils

26 September 2017

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26 September 2017

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Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors

26 September 2017

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Mechanism of Anti-α-Synuclein Immunotherapy

26 September 2017

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Cellular response of human neuroblastoma cells to α-synuclein fibrils, the main constituent of Lewy bodies

26 September 2017

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Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies

26 September 2017

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26 September 2017

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Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice

26 September 2017

1 reference

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Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy

26 September 2017

1 reference

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Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson's disease

26 September 2017

1 reference

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Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models

26 September 2017

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.

26 September 2017

1 reference

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Α-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration

26 September 2017

1 reference

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Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice

26 September 2017

1 reference

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Amyloid-ß-directed immunotherapy for Alzheimer's disease

26 September 2017

1 reference

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Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials

26 September 2017

1 reference

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Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases

26 September 2017

1 reference

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Transmission of multiple system atrophy prions to transgenic mice

26 September 2017

1 reference

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Structural and functional characterization of two alpha-synuclein strains

26 September 2017

1 reference

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α-Synuclein vaccination prevents the accumulation of parkinson disease-like pathologic inclusions in striatum in association with regulatory T cell recruitment in a rat model

26 September 2017

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Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases

26 September 2017

1 reference

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Immunotherapy for neurodegenerative diseases: focus on α-synucleinopathies

26 September 2017

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Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission

26 September 2017

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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

26 September 2017

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The amyloid state of proteins in human diseases

26 September 2017

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Vaccination for Parkinson's disease

26 September 2017

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E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment

26 September 2017

1 reference

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Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

26 September 2017

1 reference

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The propagation of prion-like protein inclusions in neurodegenerative diseases

26 September 2017

1 reference

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Molecular mechanisms of alpha-synuclein neurodegeneration

26 September 2017

1 reference

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Characterization of antibodies that selectively detect alpha-synuclein in pathological inclusions

26 September 2017

1 reference

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Insights into prion strains and neurotoxicity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: an age-related selective uptake with reversal of learning impairment

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

The biochemistry of Parkinson's disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Comparison of ethanol versus formalin fixation on preservation of histology and RNA in laser capture microdissected brain tissues

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Alpha-synuclein and neurodegenerative diseases

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Immunohistochemical and biochemical studies demonstrate a distinct profile of alpha-synuclein permutations in multiple system atrophy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Accumulation of tubular structures in oligodendroglial and neuronal cells as the basic alteration in multiple system atrophy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Proteolysis of α-synuclein fibrils in the lysosomal pathway limits induction of inclusion pathology

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

100 years of Lewy pathology

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5599040

A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28910367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0184731

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28910367%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

28910367

1 reference