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Expression of drug-metabolizing enzymes
scientific article published on October 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
review article
1 reference
stated in
Europe PubMed Central
title
Expression of drug-metabolizing enzymes
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
author name string
Guengerich FP
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
Parikh A
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
publication date
1 October 1997
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
published in
Current Opinion in Biotechnology
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
volume
8
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
issue
5
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stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
page(s)
623-628
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stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
cites work
Eukaryotic expression systems: a comparison
1 reference
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Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes
1 reference
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Optimized heterologous expression of the polymorphic human glutathione transferase M1-1 based on silent mutations in the corresponding cDNA.
1 reference
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Crossref
reference URL
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Heterologous expression, purification and characterization of rat class theta glutathione transferase T2-2
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reference URL
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Forced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme.
1 reference
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reference URL
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7 January 2021
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Glutathione transferases with novel active sites isolated by phage display from a library of random mutants
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Glubodies: randomized libraries of glutathione transferase enzymes
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Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase)
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Salmonella strains and mammalian cells genetically engineered for expression of sulfotransferases
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Baculovirus expression and characterization of catalytically active horseradish peroxidase
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Leukocyte 12-lipoxygenase: expression, purification, and investigation of the role of methionine residues in turnover-dependent inactivation and 5,8,11,14-eicosatetraynoic acid inhibition.
1 reference
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Expression, purification, and characterization of porcine leukocyte 12-lipoxygenase produced in the methylotrophic yeast, Pichia pastoris.
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High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli
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Neuronal nitric oxide synthase. Expression in Escherichia coli, irreversible inhibition by phenyldiazene, and active site topology.
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New applications of bacterial systems to problems in toxicology.
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Purification of functional recombinant P450s from bacteria.
1 reference
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Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells
1 reference
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reference URL
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7 January 2021
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Monooxygenase activity of Saccharomyces cerevisiae cells transformed with expression plasmids carrying rat cytochrome P-450MC cDNA
1 reference
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reference URL
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7 January 2021
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Expression of a functional 78,000 dalton mammalian flavoprotein, NADPH-cytochrome P-450 oxidoreductase, in Escherichia coli
1 reference
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Crossref
reference URL
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7 January 2021
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Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli
1 reference
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7 January 2021
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Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat
1 reference
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Recombinant human cytochrome P450 1A2 and an N-terminal-truncated form: construction, purification, aggregation properties, and interactions with flavodoxin, ferredoxin, and NADPH-cytochrome P450 reductase
1 reference
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Molecular engineering of microsomal P450 2a-4 to a stable, water-soluble enzyme.
1 reference
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Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes
1 reference
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Crossref
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Expression of cytochrome P450 2D6 in Escherichia coli, purification, and spectral and catalytic characterization
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Crossref
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Microsomal P450 2C3 is expressed as a soluble dimer in Escherichia coli following modification of its N-terminus
1 reference
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Identification of retained N-formylmethionine in bacterial recombinant mammalian cytochrome P450 proteins with the N-terminal sequence MALLLAVFL...: roles of residues 3-5 in retention and membrane topology
1 reference
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Crossref
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Construction of a human cytochrome P450 1A1: rat NADPH-cytochrome P450 reductase fusion protein cDNA and expression in Escherichia coli, purification, and catalytic properties of the enzyme in bacterial cells and after purification.
1 reference
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Crossref
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7 January 2021
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Expression, purification, and characterization of a catalytically active human cytochrome P450 1A2:rat NADPH-cytochrome P450 reductase fusion protein.
1 reference
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Crossref
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Molecular engineering study on electron transfer from NADPH-P450 reductase to rat mitochondrial P450c27 in yeast microsomes
1 reference
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Crossref
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The interaction of NADPH-P450 reductase with P450: an electrochemical study of the role of the flavin mononucleotide-binding domain.
1 reference
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Putidaredoxin reductase-putidaredoxin-cytochrome p450cam triple fusion protein. Construction of a self-sufficient Escherichia coli catalytic system.
1 reference
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CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4.
1 reference
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Functional high level expression of cytochrome P450 CYP2D6 using baculoviral expression systems.
1 reference
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Crossref
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Expression and coupling of human cytochrome P450 2E1 and NADPH-cytochrome P450 oxidoreductase in dual expression and co-infection systems with baculovirus in insect cells
1 reference
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Crossref
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Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells.
1 reference
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Crossref
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Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli.
1 reference
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Crossref
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The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.
1 reference
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Crossref
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Drug metabolism by Escherichia coli expressing human cytochromes P450.
1 reference
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7 January 2021
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Expression and characterization of a modified flavin-containing monooxygenase 4 from humans
1 reference
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Crossref
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Expression of the human UDP-glucuronosyltransferase UGT1*6 in Escherichia coli. Influence of bacterial signal peptides on the production and localization of the recombinant protein.
1 reference
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Crossref
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Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue
1 reference
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Crossref
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The transmembrane region of microsomal cytochrome P450 identified as the endoplasmic reticulum retention signal
1 reference
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Crossref
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The cytoplasmic and N-terminal transmembrane domains of cytochrome P450 contain independent signals for retention in the endoplasmic reticulum
1 reference
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Crossref
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Establishment of transgenic mice carrying human fetus-specific CYP3A7.
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Use of terfenadine and contraindicated drugs
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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection
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Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium
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Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.
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A new Salmonella typhimurium NM5004 strain expressing rat glutathione S-transferase 5-5: use in detection of genotoxicity of dihaloalkanes using an SOS/umu test system.
1 reference
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Development of an in situ toxicity assay system using recombinant baculoviruses
1 reference
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Crossref
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Metabolism of chlorofluorocarbons and polybrominated compounds by Pseudomonas putida G786(pHG-2) via an engineered metabolic pathway
1 reference
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7 January 2021
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Identifiers
DOI
10.1016/S0958-1669(97)80039-0
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
PubMed ID
9353222
1 reference
stated in
Europe PubMed Central
PubMed ID
9353222
retrieved
26 September 2017
ResearchGate publication ID
13876731
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