(Q41105264)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

title

Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Lindsay B Alcaraz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Bastien Kaniewski

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Celia Cintas

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Jennifer P. Morton

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Owen J Sansom

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Ulrich Valcourt

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

24

Isabelle Treilleux

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

20

Anne Couvelard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

16

Nicolas Gadot

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

Nicolas Chuvin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

David F Vincent

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Roxane M Pommier

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Johann Gout

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Cassandre Caligaris

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Karam Yacoub

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Victoire Cardot

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Elodie Roger

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Sylvie Martel

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Sophie Goddard-Léon

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Amélie Colombe

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Julie Valantin

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Emilie Servoz

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Isabelle Goddard

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Vinciane Rebours

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Stéphanie Sentis

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Pierre Dubus

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Julie Guillermet

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

publication date

31 May 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

Cellular and molecular gastroenterology and hepatology

26 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

263-282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

26 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5524227/fullTextXML

inferred from PubMed Central ID database lookup

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TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells

26 September 2017

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Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis

26 September 2017

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26 September 2017

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TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

26 September 2017

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26 September 2017

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Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.

26 September 2017

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26 September 2017

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TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

26 September 2017

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Regulation of Cellular Identity in Cancer

26 September 2017

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Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine

26 September 2017

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Reserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tract

26 September 2017

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RUNX3 Controls a Metastatic Switch in Pancreatic Ductal Adenocarcinoma

26 September 2017

1 reference

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YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

26 September 2017

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Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function

26 September 2017

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Regeneration and repair of the exocrine pancreas

26 September 2017

1 reference

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NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response

26 September 2017

1 reference

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TGF-β prevents T follicular helper cell accumulation and B cell autoreactivity

26 September 2017

1 reference

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The secret origins and surprising fates of pancreas tumors

26 September 2017

1 reference

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TGF-β: duality of function between tumor prevention and carcinogenesis.

26 September 2017

1 reference

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Perspectives of TGF-β inhibition in pancreatic and hepatocellular carcinomas

26 September 2017

1 reference

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The roles of TGFβ in the tumour microenvironment

26 September 2017

1 reference

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Pancreas organogenesis: from lineage determination to morphogenesis

26 September 2017

1 reference

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26 September 2017

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Biology and clinical applications of pancreatic cancer stem cells

26 September 2017

1 reference

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Control of cell identity in pancreas development and regeneration

26 September 2017

1 reference

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Evolution and dynamics of pancreatic cancer progression

26 September 2017

1 reference

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Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration

26 September 2017

1 reference

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The harmonies played by TGF-β in stem cell biology

26 September 2017

1 reference

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TGFβ signalling in context

26 September 2017

1 reference

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Molecular pathways in pancreatic carcinogenesis

26 September 2017

1 reference

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Pancreatitis and pancreatic cancer risk: a pooled analysis in the International Pancreatic Cancer Case-Control Consortium (PanC4).

26 September 2017

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TGF-β control of stem cell differentiation genes

26 September 2017

1 reference

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Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway

26 September 2017

1 reference

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Pancreas organogenesis: from bud to plexus to gland

26 September 2017

1 reference

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KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

26 September 2017

1 reference

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A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice.

26 September 2017

1 reference

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TGFbeta signalling: a complex web in cancer progression

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Roles of TGFbeta in metastasis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

An illustrated review of early pancreas development in the mouse.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Inactivation of Smad4 accelerates Kras(G12D)-mediated pancreatic neoplasia

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Upregulation of two BH3-only proteins, Bmf and Bim, during TGF beta-induced apoptosis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Pancreatic Adenocarcinoma

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

The conditional expression of KRAS G12D in mouse pancreas induces disorganization of endocrine islets prior the onset of ductal pre-cancerous lesions.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Development and function of murine RORγt+ iNKT cells are under TGF-β signaling control.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Inhibition of transforming growth factor beta signaling by halofuginone as a modality for pancreas fibrosis prevention

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Protection of cerulein-induced pancreatic fibrosis by pancreas-specific expression of Smad7.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Amelioration of pancreatic fibrosis in mice with defective TGF-beta signaling

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Inhibition of transforming growth factor beta decreases pancreatic fibrosis and protects the pancreas against chronic injury in mice

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

An X-linked GFP transgene reveals unexpected paternal X-chromosome activity in trophoblastic giant cells of the mouse placenta

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5524227

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

19 August 2018

1 reference

12 December 2020

Transplantation of azaserine-induced carcinomas of pancreas in rats

1 reference

12 December 2020

1 reference

12 December 2020

Generation of mice with conditionally activated transforming growth factor beta signaling through the TβRI/ALK5 receptor

1 reference

12 December 2020

Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression

1 reference

12 December 2020

TGF-beta 1 influences the relative development of the exocrine and endocrine pancreas in vitro

1 reference

12 December 2020

10.1016/J.JCMGH.2017.05.005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28752115%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

28752115

1 reference