(Q41113531)

English

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

scientific article published on 23 November 2010

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scholarly article

1 reference

Europe PubMed Central

26 September 2017

Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease (English)

1 reference

Europe PubMed Central

26 September 2017

1 reference

based on heuristic

inferred from title

author name string

Francesca L'Episcopo

1

1 reference

Europe PubMed Central

26 September 2017

Cataldo Tirolo

2

1 reference

Europe PubMed Central

26 September 2017

Salvatore Caniglia

3

1 reference

Europe PubMed Central

26 September 2017

Nunzio Testa

4

1 reference

Europe PubMed Central

26 September 2017

Pier A Serra

5

1 reference

Europe PubMed Central

26 September 2017

Francesco Impagnatiello

6

1 reference

Europe PubMed Central

26 September 2017

Maria C Morale

7

1 reference

Europe PubMed Central

26 September 2017

Bianca Marchetti

8

1 reference

Europe PubMed Central

26 September 2017

publication date

23 November 2010

1 reference

Europe PubMed Central

26 September 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

26 September 2017

7

1 reference

Europe PubMed Central

26 September 2017

83

1 reference

Europe PubMed Central

26 September 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-7-83

0 references

Glia as a turning point in the therapeutic strategy of Parkinson's disease.

1 reference

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Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis

1 reference

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27 September 2017

Ageing, neurodegeneration and Parkinson's disease

1 reference

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Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

1 reference

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A dual-hit animal model for age-related parkinsonism

1 reference

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Immune activation in brain aging and neurodegeneration: too much or too little?

1 reference

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NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies

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A comparison of model-based (2D) and design-based (3D) stereological methods for estimating cell number in the substantia nigra pars compacta (SNpc) of the C57BL/6J mouse

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Neuroinflammation in Parkinson's disease: a target for neuroprotection?

1 reference

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Intrastriatal lipopolysaccharide injection induces parkinsonism in C57/B6 mice

1 reference

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Evolution of nonsteroidal anti-inflammatory drugs (NSAIDs): cyclooxygenase (COX) inhibition and beyond

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Astrocyte-secreted GDNF and glutathione antioxidant system protect neurons against 6OHDA cytotoxicity

1 reference

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Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

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Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

1 reference

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1 reference

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Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

1 reference

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1 reference

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Glial reactions in Parkinson's disease

1 reference

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1 reference

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Therapeutic approaches to inflammation in neurodegenerative disease

1 reference

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Non-steroidal anti-inflammatory drugs in Parkinson's disease

1 reference

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Protocol for the MPTP mouse model of Parkinson's disease

1 reference

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Inflammation as a causative factor in the aetiology of Parkinson's disease

1 reference

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Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism

1 reference

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1 reference

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Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

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Nonsteroidal anti-inflammatory drugs in Parkinson's disease: possible involvement of quinone formation

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Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.

1 reference

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1 reference

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1 reference

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To be or not to be (inflamed)--is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?

1 reference

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1 reference

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1 reference

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1 reference

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Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

1 reference

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1 reference

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1 reference

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1 reference

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Novel anti-inflammatory therapy for Parkinson's disease.

1 reference

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1 reference

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1 reference

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1 reference

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Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats

1 reference

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Functional consequences of dopaminergic degeneration in Parkinson's disease.

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1 reference

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Adaptive changes in the nigrostriatal pathway in response to increased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration in the mouse

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19 August 2018

Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse.

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19 August 2018

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19 August 2018

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Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice

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19 August 2018

Indomethacin protects against neurodegeneration caused by MPTP intoxication in mice.

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19 August 2018

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Involvement of inducible nitric oxide synthase in inflammation-induced dopaminergic neurodegeneration

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19 August 2018

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

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19 August 2018

Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000390

19 August 2018

NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000390

19 August 2018

Strain-dependent susceptibility to MPTP and MPP(+)-induced parkinsonism is determined by glia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000390

19 August 2018

The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000390

19 August 2018

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000390

19 August 2018

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000390

30 September 2018

Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: pivotal role for glia-neuron interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into COX-2 biology and inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A diclofenac derivative without ulcerogenic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of nuclear population from microtome sections

1 reference

https://pubmed.ncbi.nlm.nih.gov/21092260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-7-83

1 reference

Europe PubMed Central

26 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

26 September 2017

1 reference

Europe PubMed Central

26 September 2017

ResearchGate publication ID

0 references

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