(Q41116023)

27 September 2017

Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation (English)

1 reference

27 September 2017

Peter M Bowers

1

1 reference

27 September 2017

Tamlyn Y Neben

2

1 reference

27 September 2017

Geoffery L Tomlinson

3

1 reference

27 September 2017

Jennifer L Dalton

4

1 reference

27 September 2017

Larry Altobell

5

1 reference

27 September 2017

Xue Zhang

6

1 reference

27 September 2017

John L Macomber

7

1 reference

27 September 2017

Betty F Wu

8

1 reference

27 September 2017

Rachelle M Toobian

9

1 reference

27 September 2017

Audrey D McConnell

10

1 reference

27 September 2017

Petra Verdino

11

1 reference

27 September 2017

Betty Chau

12

1 reference

27 September 2017

Robert A Horlick

13

1 reference

27 September 2017

David J King

14

1 reference

27 September 2017

language of work or name

English

0 references

publication date

25 January 2013

1 reference

Journal of Biological Chemistry

27 September 2017

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

27 September 2017

288

1 reference

27 September 2017

11

1 reference

27 September 2017

7688-7696

1 reference

High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Antibody-based therapeutics to watch in 2011.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Isolating and engineering human antibodies using yeast surface display

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Isolation of anti-CD22 Fv with high affinity by Fv display on human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Cutting edge: DGYW/WRCH is a better predictor of mutability at G:C bases in Ig hypermutation than the widely accepted RGYW/WRCY motif and probably reflects a two-step activation-induced cytidine deaminase-triggered process

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

IMGT-ONTOLOGY and IMGT databases, tools and Web resources for immunogenetics and immunoinformatics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Somatic hypermutation of the AID transgene in B and non-B cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Improving antibody affinity by mimicking somatic hypermutation in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Antibody humanization using monovalent phage display

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Replacing the complementarity-determining regions in a human antibody with those from a mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

A humanized antibody that binds to the interleukin 2 receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Selection of phage antibodies by binding affinity. Mimicking affinity maturation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

A novel solid phase technology for high-throughput gene synthesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

A molecular immunology approach to antibody humanization and functional optimization.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Gene segments encoding transmembrane carboxyl termini of immunoglobulin gamma chains

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Reshaping human antibodies: grafting an antilysozyme activity

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597809

Selection of phage antibodies by binding affinity

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.445502

Three distinct types of monoclonal antibodies after long-term immunization of rats with mouse nerve growth factor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23355464

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

"Superhumanized" antibodies: reduction of immunogenic potential by complementarity-determining region grafting with human germline sequences: application to an anti-CD28

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23355464

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.445502

1 reference

27 September 2017

1 reference

27 September 2017

PubMed publication ID

23355464

1 reference