(Q41194895)

28 September 2017

Structural and functional characterization of a specific antidote for ticagrelor (English)

1 reference

28 September 2017

18

Sven Nylander

1 reference

28 September 2017

Andrew Buchanan

1

1 reference

28 September 2017

Philip Newton

2

1 reference

28 September 2017

Susanne Pehrsson

3

1 reference

28 September 2017

Tord Inghardt

4

1 reference

28 September 2017

Thomas Antonsson

5

1 reference

28 September 2017

Peder Svensson

6

1 reference

28 September 2017

Tove Sjögren

7

1 reference

28 September 2017

Linda Öster

8

1 reference

28 September 2017

Annika Janefeldt

9

1 reference

28 September 2017

Ann-Sofie Sandinge

10

1 reference

28 September 2017

Feenagh Keyes

11

1 reference

28 September 2017

Mark Austin

12

1 reference

28 September 2017

Jennifer Spooner

13

1 reference

28 September 2017

Peter Gennemark

14

1 reference

28 September 2017

Mark Penney

15

1 reference

28 September 2017

Garnet Howells

16

1 reference

28 September 2017

Tristan Vaughan

17

1 reference

28 September 2017

language of work or name

English

0 references

publication date

18 March 2015

1 reference

28 September 2017

1 reference

28 September 2017

125

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28 September 2017

22

1 reference

28 September 2017

3484-3490

1 reference

2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Adenosine-mediated effects of ticagrelor: evidence and potential clinical relevance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

A high-yielding CHO transient system: coexpression of genes encoding EBNA-1 and GS enhances transient protein expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

A specific antidote for dabigatran: functional and structural characterization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Ticagrelor versus clopidogrel in patients with acute coronary syndromes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Ticagrelor-associated bleeding in a patient undergoing surgery for acute type A aortic dissection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Antidotes edge closer to reversing effects of new blood thinners

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4447862

Low platelet reactivity is recovered by transfusion of stored platelets: a healthy volunteer in vivo study

19 August 2018

1 reference

12 December 2020

Inefficacy of platelet transfusion to reverse ticagrelor

1 reference

12 December 2020

From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis

1 reference

12 December 2020

Use of PER977 to reverse the anticoagulant effect of edoxaban

1 reference

12 December 2020

Determination of unbound ticagrelor and its active metabolite (AR-C124910XX) in human plasma by equilibrium dialysis and LC-MS/MS

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies

1 reference

12 December 2020

Is platelet transfusion efficient to restore platelet reactivity in patients who are responders to aspirin and/or clopidogrel before emergency surgery?

1 reference

12 December 2020

10.1182/BLOOD-2015-01-622928

Identifiers

DOI

1 reference

28 September 2017

1 reference

28 September 2017

1 reference