(Q41249289)

English

Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Alteration in P-glycoprotein functionality affects intrabrain distribution of quinidine more than brain entry-a study in rats subjected to status epilepticus by kainate (English)

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

status epilepticus

1 reference

based on heuristic

inferred from title

author name string

Stina Syvänen

1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Maarten Schenke

2

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Dirk-Jan van den Berg

3

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Rob A Voskuyl

4

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Elizabeth C de Lange

5

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

language of work or name

0 references

publication date

4 January 2012

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

The AAPS Journal

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

14

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

87-96

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

https://scigraph.springernature.com/pub.10.1208/s12248-011-9318-1

0 references

(R)-[11C]verapamil PET studies to assess changes in P-glycoprotein expression and functionality in rat blood-brain barrier after exposure to kainate-induced status epilepticus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

28 September 2017

Targeting regulation of ABC efflux transporters in brain diseases: a novel therapeutic approach.

1 reference

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Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

1 reference

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28 September 2017

Methodologies to assess brain drug delivery in lead optimization

1 reference

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28 September 2017

Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection

1 reference

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28 September 2017

Brain endothelial cells and the glio-vascular complex

1 reference

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28 September 2017

Tariquidar-induced P-glycoprotein inhibition at the rat blood-brain barrier studied with (R)-11C-verapamil and PET.

1 reference

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28 September 2017

Peripheral nerve pericytes originating from the blood-nerve barrier expresses tight junctional molecules and transporters as barrier-forming cells

1 reference

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28 September 2017

On the rate and extent of drug delivery to the brain.

1 reference

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28 September 2017

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

1 reference

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28 September 2017

Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms

1 reference

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28 September 2017

Selective and persistent upregulation of mdr1b mRNA and P-glycoprotein in the parahippocampal cortex of chronic epileptic rats

1 reference

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28 September 2017

The role of positron emission tomography with [18F]fluorodeoxyglucose in the evaluation of the epilepsies

1 reference

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28 September 2017

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

28 September 2017

Methodological issues in microdialysis sampling for pharmacokinetic studies

1 reference

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28 September 2017

Clinical aspects and biological bases of drug-resistant epilepsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

28 September 2017

MDR1 gene expression in brain of patients with medically intractable epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

28 September 2017

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

28 September 2017

Modification of seizure activity by electrical stimulation. 3. Mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

14 June 2018

Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentratio

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19 August 2018

Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

19 August 2018

Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

19 August 2018

Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

19 August 2018

Conditional weighted residuals (CWRES): a model diagnostic for the FOCE method.

1 reference

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19 August 2018

AAPS-FDA workshop white paper: microdialysis principles, application and regulatory perspectives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

19 August 2018

NONMEMory: a run management tool for NONMEM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

19 August 2018

Transient increase of P-glycoprotein expression in endothelium and parenchyma of limbic brain regions in the kainate model of temporal lobe epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281999

19 August 2018

Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy.

1 reference

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In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats

1 reference

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Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections

1 reference

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Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: assessment of a rat model of temporal lobe epilepsy

1 reference

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Ionic composition of microdialysis perfusing solution alters the pharmacological responsiveness and basal outflow of striatal dopamine

1 reference

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A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/22215264

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based on heuristic

inferred from PubMed ID database lookup

Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22215264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microdialysis probes calibration: gradient and tissue dependent changes in no net flux and reverse dialysis methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/22215264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methodological considerations of intracerebral microdialysis in pharmacokinetic studies on drug transport across the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/22215264

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1208/S12248-011-9318-1

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

28 September 2017

ResearchGate publication ID

0 references

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